Oh Oh Oh Ozempic For Our Oh Oh Oh Obese Cats? It’s Close To Reality

In apocalyptic news for house cats everywhere, a pharmaceutical company is kicking off a trial of a GLP-1 drug for felines.

If cats could read newspapers, chances are they’d be gripped by a cold terror right about now, wondering if they’re among the unfortunates to have their yums curtailed by the same weight loss drugs their humans have been gobbling.

As the New York Times reports, a biopharma company headquartered in San Francisco, Okava Pharmaceuticals, is about to begin a trial to determine if GLP-1 drugs can help our chonksters slim down. More than 60 percent of American pets are packing extra pounds, the Times notes, while consequences like diabetes are shortening the lifespans and reducing quality of life for felines and canines.

“It is our belief that the condition of obesity, the condition of being overweight, is by far the number one most significant preventative health challenge in all of veterinary medicine,” Okava founder and CEO Michael Klotsman told the paper.

The upcoming study will include 50 cats. Most will receive a GPL-1 medication while a control group — about one third of the cats — will be given a placebo.

Since cats aren’t exactly known for being cooperative when it comes to taking oral medicine and weekly injections at a veterinary office are impractical, Okava has developed a system with a patch about the size of a microchip that will dispense the weight loss drugs over six months before a tiny cartridge needs to be replaced.

If all goes well with the trial, Okava will seek FDA approval and address other obstacles like convincing caretakers that their little pals can benefit from the feline version of Ozempic, Mounjaro and Wegovy.

That may be easier said than done considering our relationships with our furry friends and the role food plays in things like training, bonding and every day life

For lots of cat caretakers “their main way that they interact with and show their love to their pet often revolves around food,” Dr. Maryanne Murphy, a veterinary nutritionist at the University of Tennessee, told the Times.

How could the dynamic between cat and human change if the flow of yums is reduced to meals only? Will training — for everything from walking on a harness, to entering a carrier and fun tricks like high fives — still work if the reward is just a bit of encouragement or a scratch behind the ear?

An earlier weight loss drug developed for dogs, Slentrol, did not catch on because, as one veterinarian noted, “the main way [people] interacted with their pet was by feeding them, and seeing their excitement and happiness when they were eating the food.”

There’s also the not-so-small matter of cost. GLP-1 drugs are in high demand, and they’re expensive. One in eight Americans has taken Ozempic or one of its competitors. At times, the demand has threatened availability for diabetics, for whom the drugs were developed in the first place.

If the trials are successful and the GLP-1 drugs for pets gain FDA approval — which would require a series of much larger scale, more rigorous studies — the company hopes to offer them to consumers at a cost of about $100 per month per pet.

Even if this iteration of the drug fails, it’s unlikely to derail the larger effort. Vets have been prescribing tiny doses of the human version to cats with diabetes, and perhaps most telling of all, pet obesity continues to rise despite years of efforts by the veterinarian community to get people to play with their pets more and feed them less.

As Dr. Ernie Ward, a veterarian and founder of the Association for Pet Obesity Prevention, told the paper: “We haven’t moved the needle.”


And now we check in with our correspondent, Buddy the Cat. Buddy, what do you think about the possibility of GLP-1 for your species and the end of the proverbial gravy train?

Buddy? Bud? Are we having technical difficulties?

I’m sorry, ladies and gentlemen, we can’t find Buddy the Cat. We’ll resume this segment if and when we manage to locate him.

Memo From Buddy The Cat, Re: My Human’s Failure To Buy Me A Roomba

Buddy the Cat wants his human to provide him with alternatives to his long-desired Roomba. Nothing fancy, of course.

Sept. 1, 2025 (11 A.B., or After Buddy)
To: Big Buddy
From: Little Buddy

Dear Buddy the Larger,

Since you have failed to secure a Roomba as my personal steed, as per my repeated demands, I have commissioned several other ideas for my personal conveyance.

Please find the enclosed image of a less complex, human-powered method of mobility fitting my station and status as an awesome feline. I have also attached an image of an appropriate seat designated for my use: humble yet regal, comfortable yet authoritative, offering supplicants the chance to to approach my feline personage while also clearly delineating the difference in power between myself, on my raised dais, and the lowly humans who seek my favor.

Note the dog pelt as a carpet beneath my throne…er, I mean my chair. Any dog who seeks an audience will be reminded that I’m, like, a jaguar and stuff, and they’d better be sufficiently deferential and pay tribute with delicious gifts.

Your friend and master,

Buddy

This design eschews all the complex and expensive machinery of a Roomba for good, old-fashioned human labor. I will require six Royal Buddy Guards: four to carry me at normal times, and six to carry me after I’ve feasted. I told the concept artist not to go too crazy with the ornamentation. Nothing too ostentatious, as you can see.

This design, inspired by Kublai Khan’s court in Khanbaliq (Cambulac), his winter capital. Unfortunately I couldn’t find much about the throne in his summer capital, Xanadu, but I have commissioned a designer to cook up something appropriate and will forward that to you shortly as well.

As you can see, nothing particularly fancy here, just good, sturdy, common sense necessities. I’m sure you’ll get right on it.

Buddy Issues Sanctions Against Human In Diplomatic Row Over Meal Variety

Dissatisfied with the limited variety of flavors and textures in his regular meal rotation, Buddy the Cat unveiled a sweeping new sanctions package designed to force his human to do better.

NEW YORK — Angry over his servant’s failure to broaden his selection of regular meals, Buddy the Cat announced new sanctions on Saturday aimed at forcing the uncooperative human to comply.

“President Buddy feels he’s been patient and magnanimous in dealing with his human’s shortcomings, but even a saint’s patience has limits,” Buddy’s spokesman told reporters. “This new sanctions package clearly communicates President Buddy’s disappointment and ensures swift compliance.”

The sanctions include prohibitive measures against sleep duration and quality, with Buddy promising to yowl at regular intervals and to wake his human by slapping him in the face every morning.

In addition, affection will be cut by 50 percent, increasing to 75 percent within two weeks if there is no improvement in the variety of flavors and textures of wet food served to Buddy.

“Buddy has made it clear that he expects more than a simple rotation of turkey, chicken and salmon pate,” the feline’s spokesman said. “He wants chunky tuna, he wants beef, he wants shredded duck served in gravy.”

President Buddy had threatened to pull his ambassadors and enact legislation declaring all shoes, sneakers and boots as legal litter boxes if the cheese sharing protocol was not observed. Credit: Wikimedia Commons

The latest round of sanctions follows the Buddesian Diplomatic Crisis of 2023, when Buddy threatened to begin using his Big Buddy’s shoes, boots and sneakers as litter boxes in retaliation for the latter failing to “equitably share cheese as per article IV, sub-clause C of the gastronomic distribution protocol.”

All-out war was avoided when both parties agreed that Little Buddy’s share of Gouda, American, provolone and other cheeses, excluding ricotta, feta and mozzarella, would be increased by 15 percent.

New Yorkers Barricade Themselves In Homes After Buddy The Cat Reported Loose On Streets

The feline laid waste to entire restaurants and food stalls during his rampage through the city, sending residents running for cover.

NEW YORK — The island of Manhattan was brought to a standstill this week after a massive and menacing wildcat was seen stalking the streets.

The first reports came in Wednesday afternoon after panicked callers told 911 dispatchers a “yuge gray tiger” had barreled into Gray’s Papaya on Broadway and 72nd, gorging itself on the eatery’s famous hot dogs.

Social media posts timestamped an hour later showed clips of the terrifying felid running full speed toward an Atomic Wings, where it tore through the entire inventory of chicken and hamburgers.

“Holy [bleep], that’s not a tiger, that’s a kaiju!” one TikTok user said in a video uploaded to the popular social media site.

The TikToker’s footage showed the gargantuan cat emerge from the Atomic Wings, hot sauce dribbling down the fur on its chin, and belch with such force that car alarms began shrieking in a three-block radius.

“We’re receiving reports that the colossal cat’s name is Buddy, and he escaped earlier Wednesday from an apartment where some lunatic was illegally keeping him as a pet,” Fox News’ Brett Baier told viewers. “A law enforcement source says the man has been taken into custody as a person of interest, and will likely face charges of harboring a dangerous wild animal.”

Detectives were seen escorting the cuffed man, who screamed incoherently that Buddy is allegedly “just a house cat.”

“He invented a laser that increased his size 70 fold!” the deranged man shouted as news cameras followed the detectives from the squad car. “He’s a wimp! Rustle a paper bag! Bring out a vacuum! You’ll see!”

New York Mayor Eric Adams dismissed the man’s claims as “the rantings of a clearly insane person,” and assured residents that the so-called Buddinese tiger would be “swiftly caught and dealt with by the brave men and women of the NYPD.”

“You’ll be able to make your dinner reservations, folks,” Adams said as an interpreter translated his words into American sign language behind him. “In the meantime, keep your doors and windows locked, and don’t cook anything pungent. This is a hungry beast who has eaten his way through dozens of restaurants.”

Police had set up a trap in midtown, with more than 900 pounds of roast turkey and baseball-size Temptations to lure the rampaging tiger.

Turkey trap!
The ill-fated turkey trap.

But the plan went horribly wrong on Thursday evening when the tiger approached.

“This beast is truly gargantuan!” ABC reporter Stephan Kim whispered during a live broadcast. “Each footfall seems to shake the earth. Look! The concrete is cracking and spidering beneath his paws as if it were brittle ice!”

The Buddinese Tiger stopped, sniffed, then launched himself at the pile of turkey, not even registering the tranquilizer darts fired by NYPD snipers stationed on top of nearby buildings until one hit him in the buttock.

The vicious cat roared and looked as if he would take down the building where the offending officer stood until he was distracted by the smell of Peruvian food wafting from a nearby Pio Pio.

“Arroz chaufa!” the tiger yelled, turning his enormous frame and stomping off into the distance.

City leaders admitted they’d underestimated the threat and had officially requested the National Guard, which was being mobilized late Thursday evening.

But an NYPD detective, speaking on condition of anonymity, said authorities were beginning to reconsider the claim that the rampaging animal could be a house cat.

“One of our officers called him a ‘good boy’ in a last, desperate attempt to save his own life when he was cornered by the beast,” the detective said. “To his surprise, the tiger pounced on him, licked his face, then went on his way, repeating ‘I’m a good boy!’ Maybe there’s some truth to this claim about the size-increasing laser.”

Rep. Marjorie Taylor-Greene of Georgia siezed on the story, posting a message on X claiming credit for “warnin’ ya’ll about these space lasers.”

“One of these lasers has turned a cuddly little house cat into a terrifying tiger,” Greene wrote. “So who’s a conspiracy theorist now?”

This Cat Pretends To Be Asleep To Steal His Human’s Food

The video is thoroughly amusing, but it also illustrates profound truths about feline intelligence, showing cats understand a lot more than people often give them credit for.

I’m loving this video of a sneaky orange tabby pretending to snooze while helping himself to his human’s food.

Little dude lays down and closes his eyes, then slowly reaches a paw out to the cap of an ice cream container, which has a glob of the good stuff on it. He checks to make sure the coast is clear by opening his eyes just a tiny bit, then slowly moves the cap over incrementally, pausing at intervals to make sure he’s still unobserved. (It looks like his human set her phone to record, then left the room so her little buddy thought no eyes were on him).

@caitlyn_davis34

“If I pretend to be alseep and move REAL slow, she won’t notice” #OrangeCatActivities #DontBeSuspicious

♬ Stealthy mischief(1088178) – KBYS

Aside from being hilarious and cute, this short clip actually illustrates something profound: Cats are much more intelligent than people usually give them credit for.

Consider the fact that to pull this off, the cat needs to be self-aware, and he needs to possess theory of mind. In other words, this cat understands he and his human have different perspectives, know different things, and that if he can move stealthily and appear to innocently nap, he can get away with eating some ice cream.

That may not seem like a big deal at first, but it means the cat understands humans can be deceived, and he understands how to do it. He cannot possibly know we have technology that can record him while we’re not looking, so that’s not a strike against him. There are plenty of things we don’t understand about animals, and we’re supposed to be the more intelligent species.

To truly appreciate how profound this is, consider that human children do not fully possess theory of mind until they’re four or five years old! That’s when they begin to appreciate the fact that other people have internal thought processes and emotions — even if they can’t articulate that — and, crucially, that what a person thinks she knows may not align with reality.

Footage like this goes well beyond refuting the old, debunked claim that animals like cats are biological automatons without thoughts or feelings. It shows they are in full possession of the cognitive tools that form the basis for higher modes of thinking. Again, while some people might hear that and say “What’s the big deal?”, it destroys all arguments that animals don’t have emotions or don’t understand what’s happening to them when humans mistreat them.

It also shows that cats are at least as intelligent as young children in all the ways that matter. They cannot verbalize their thoughts and feelings, but that has no bearing on their existence. After all, no one would argue that a child doesn’t have feelings simply because he’s unable to speak.

Lastly, there’s one more important lesson here: hide your ice cream from your fluffy pals!

Top image via Pexels.