In apocalyptic news for house cats everywhere, a pharmaceutical company is kicking off a trial of a GLP-1 drug for felines.
If cats could read newspapers, chances are they’d be gripped by a cold terror right about now, wondering if they’re among the unfortunates to have their yums curtailed by the same weight loss drugs their humans have been gobbling.
As the New York Times reports, a biopharma company headquartered in San Francisco, Okava Pharmaceuticals, is about to begin a trial to determine if GLP-1 drugs can help our chonksters slim down. More than 60 percent of American pets are packing extra pounds, the Times notes, while consequences like diabetes are shortening the lifespans and reducing quality of life for felines and canines.
“It is our belief that the condition of obesity, the condition of being overweight, is by far the number one most significant preventative health challenge in all of veterinary medicine,” Okava founder and CEO Michael Klotsman told the paper.
The upcoming study will include 50 cats. Most will receive a GPL-1 medication while a control group — about one third of the cats — will be given a placebo.
Since cats aren’t exactly known for being cooperative when it comes to taking oral medicine and weekly injections at a veterinary office are impractical, Okava has developed a system with a patch about the size of a microchip that will dispense the weight loss drugs over six months before a tiny cartridge needs to be replaced.
If all goes well with the trial, Okava will seek FDA approval and address other obstacles like convincing caretakers that their little pals can benefit from the feline version of Ozempic, Mounjaro and Wegovy.
That may be easier said than done considering our relationships with our furry friends and the role food plays in things like training, bonding and every day life
For lots of cat caretakers “their main way that they interact with and show their love to their pet often revolves around food,” Dr. Maryanne Murphy, a veterinary nutritionist at the University of Tennessee, told the Times.
How could the dynamic between cat and human change if the flow of yums is reduced to meals only? Will training — for everything from walking on a harness, to entering a carrier and fun tricks like high fives — still work if the reward is just a bit of encouragement or a scratch behind the ear?
An earlier weight loss drug developed for dogs, Slentrol, did not catch on because, as one veterinarian noted, “the main way [people] interacted with their pet was by feeding them, and seeing their excitement and happiness when they were eating the food.”
There’s also the not-so-small matter of cost. GLP-1 drugs are in high demand, and they’re expensive. One in eight Americans has taken Ozempic or one of its competitors. At times, the demand has threatened availability for diabetics, for whom the drugs were developed in the first place.
If the trials are successful and the GLP-1 drugs for pets gain FDA approval — which would require a series of much larger scale, more rigorous studies — the company hopes to offer them to consumers at a cost of about $100 per month per pet.
Even if this iteration of the drug fails, it’s unlikely to derail the larger effort. Vets have been prescribing tiny doses of the human version to cats with diabetes, and perhaps most telling of all, pet obesity continues to rise despite years of efforts by the veterinarian community to get people to play with their pets more and feed them less.
As Dr. Ernie Ward, a veterarian and founder of the Association for Pet Obesity Prevention, told the paper: “We haven’t moved the needle.”
And now we check in with our correspondent, Buddy the Cat. Buddy, what do you think about the possibility of GLP-1 for your species and the end of the proverbial gravy train?
Buddy? Bud? Are we having technical difficulties?
I’m sorry, ladies and gentlemen, we can’t find Buddy the Cat. We’ll resume this segment if and when we manage to locate him.
Buddy’s Cat Café and Catnip Lounge has become a neighborhood fixture where feline lovers can enjoy their favorite caffeinated beverages while lavishing snacks and catnip on Buddy himself.
NEW YORK — When Buddy’s Cat Café and Catnip Lounge first opened its doors in late 2023, skeptics were quick to predict its demise.
“A cat cafe featuring only one cat sounds more like the selfish plot of the proprietor feline and less like a legitimate cat cafe experience,” the New York Times sniffed, while the New York Post derided the venture as “one chubby cat’s ludicrous scheme to gorge on endless snacks and catnip while customers line up to shower him with affection.”
Two years later, with a 4.8 out of 5 rating on Google and hundreds of regulars, Buddy’s Cat Café has not only been a success, it’s inspired other felines to open their own single-cat locations.
Mrs. Nakamura watches her students interact with Buddy, affectionately known to them as Badi-chan.
Mrs. Tomoko Nakamura, a teacher at the Japanese Academy of Manhattan, has been taking her class to Buddy’s since the cafe opened.
“Badi-chan very handsome and charming,” Mrs. Nakamura said, smiling as her students giggled and offered an array of crunchy treats to the lounging feline. “All my students love him!”
Sisters Dierdre and Stephanie Sullivan are regulars who say they take their kids to Buddy’s almost weekly.
“Madisyn, Skyelarr and Jaxon just love little Buddy,” Stephanie Sullivan said, calling other cat cafes “a tragedeigh in comparison.”
Buddy and friends during a Tabletop Tuesdays gathering at Buddy’s Cat Café and Catnip Lounge.
Since its opening, Buddy’s has featured an array of themed nights that cater to regulars with shared interests.
On Saturdays a lively crowd of people wearing perms, neon clothes and big shoulder pads flock to the cafe for Retro 80s Night. Sunday crowds gather to watch football with Buddy on the big screen TV, and Tabletop Tuesdays cater to miniature wargamers, with Buddy and his regulars continuing long-running campaigns in Dungeons and Dragons and Warhammer 40K.
One of the most popular themed nights is Freestyle Fridays, when local rappers and hip hop heads gather to spit bars, smoke blunts and collaborate on beats.
DJ Rashid, center, jubilantly hoists Buddy while the others cheer on a recent Freestyle Friday at Buddy’s Cat Cafe.Buddy after indulging in too much catnip on Freestyle Friday.
Da Ill Collektah, a local underground emcee, rolls catnip blunts for the tabby proprietor so he can fully participate in the levity.
“Oh, that’s good ish!” Buddy said on a recent Friday as he exhaled a nimbus cloud of ‘nip smoke to cheers from the assembled hip hop heads.
“Watch out!” beatsmith Biggity Biggity Bryce exclaimed. “Buddy gonna bless us with a fiyah freestyle!”
Lysander The Lyrical Destroyer, a Brooklyn emcee and longtime “associate” of Buddy, said no other cat cafe could hope to compete.
“Buddy’s cafe got the freshest jams, the livest atmosphere, and the bang bang boogie don’t stop the boogie,” he noted. “But most of all, it’s got Buddy.”
Bodega cats are the stars of a popular online series and could soon become legal in New York, where they’ve helped keep delis and small groceries rodent-free for as long as such places have existed.
Although it’s way too early to celebrate, Pennsylvania could become the fourth state to outlaw cruel declawing procedures after two lawmakers there introduced a new bill.
The Pennsylvania declawing ban proposal closely mirrors laws already passed in New York, Maryland and Massachusetts, and would outlaw the procedure except in cases where it’s medically necessary. (Although extremely rare, sometimes cats suffer from cancer of the nail bed and other maladies that necessitate surgery, but that’s a far cry from the elective declawing currently legal in 47 states.)
The state’s Veterinary Medical Association, the usual villain in these situations, is opposed to the ban. State veterinary medical associations argue that outlawing the procedure — which amputates a cat’s toes up to the first knuckle — would limit options for veterinarians and caretakers.
The veterinary medical associations, which contrary to their names do not represent all or even most veterinarians, also claim that declaw bans lead to more surrenders, but that claim has been repeatedly debunked by statistics from states and municipalities where bans have passed. In each of those cases, surrenders actually decreased, which is not a surprise to those who understand declawing, rather than “solving” any behavioral issues, actually causes cats to lash out even more because of the suffering they endure from the mutilation.
Here in New York, the Veterinary Medical Association successfully prevented declawing bans from making it out of committee for years, despite organizations like the Humane Society, SPCA, Alley Cat Allies and others wholeheartedly opposing elective declawing. Each state VMA buys influence with campaign donations, and relies on the lawmakers they support to kill declawing bans. Let’s hope Pennsylvania’s Veterinary Medical Association proves less adept at derailing that state’s bill.
The Last Cat of the Skies: The Iconic F-14 Tomcat
When I was a kid, the two Dream Machines that adorned posters on my wall were the Lamborghini Countach and the F-14 Tomcat. The Countach remains a car without equal with its inimitable, angular design that still manages to look futuristic more than half a century since the first models rolled out of the factory.
The twin-engine Tomcat is kind of like the Countach of fighter jets with its variable wing geometry, prominently angular air intakes and unique silhouette that makes it easy to distinguish even from the ground.
A Tomcat from the Nimitz-class aircraft carrier USS Theodore Roosevelt (CVN 71) during a combat flight over the Persian Gulf in 2005. Credit: U.S. Air Force photo by Tech. Sgt. Rob Tabor
Grumman’s air superiority fighter was immortalized in pop culture when Tom Cruise’s ace fighter pilot, Maverick, flew the aircraft in 1986’s Top Gun, and the Tomcat enjoyed a nostalgic encore in 2022’s excellent Top Gun: Maverick, displaying its staying power in a film that also heavily featured newer aircraft like the F-18 Super Hornet and the sixth generation prototype “Darkstar,” based on Lockheed Martin’s secretive SR-72.
The F-14 is the last of Grumman’s “cat” aircraft, after the Wildcat and Hellcat, and while it no longer fills a role in the US military, it remains a potent weapon for other countries half a century since its first flight. You can read all about the Tomcat in The Aviationist’s new feature here.
The Tomcat’s variable wings were a technological marvel when the aircraft was first released. The wings are swept forward for takeoff and landing, and typically swept backward during high speed, high altitude flight, allowing the fighter to maneuver in ways other aircraft could not. The wings can also shift to an asymmetrical configuration, allowing for unique capabilities in flight.
New York’s deli cats get their say
Bodega cats, longtime fixtures of New York’s answer to grocery stores, are enjoying a moment thanks to a major push to finally legalize their presence, and popular social media accounts featuring photographs of the beloved mousers keeping watch over their stores and snoozing in snack aisles.
A bodega cat in New York takes a siesta from his usual napping, eating and rodent-hunting duties. Credit: Wikimedia Commons
Now the New York Times has a feature on the popular TikTok series Shop Cats, which features “interviews” with the neighborhood felines.
Like Buddy, they seem to have an odd fascination with Mao Zedong, and their answers don’t make much sense, but that’s part of their charm. Check it out here.
Entering its sixth year as the most incredibly awesome cat blog in the universe, PITB continues to chronicle the amazing adventures of Buddy the Cat.
It looks like 2025 is shaping up to be quite a year!
Flow won an Oscar, the Yankees are primed for mediocrity, this is the year Nostradamus predicted we’d get those awesome hoverboards from Back To The Future, and PITB will turn six years old in the summer!
Can you believe it? Six years of thrilling millions of readers with stories of Buddy’s incredible adventures, covering the most important cat news and setting all the hot new trends in the cat world!
LITTLEBUDDYTHECAT.COM: The elegant choice for discerning cat lovers.
Critics have lavished praise on PITB:
“You won’t find two more reprehensible characters. The ill-mannered cat who’s always hatching ludicrous schemes and the human who glorifies him. They don’t have two neurons to rub together between them.” – WIRED
“Incredible! Buddy the Cat is the most dashing, dapper and daring feline on the planet, and his fans are fortunate to read about his thrilling exploits!” – Buddy Monthly (starred review)
“Two of the worst representatives of their respective species. Fate smiled cruelly upon the world when these two joined forces. Thankfully their epic incompetence prevents them from taking over.” – The Guardian
“A titan of the feline world and his human sidekick, the Buddies join forces — and combine their considerable mental resources — for the betterment of feline- and mankind. Is there anything Buddy can’t do? That’s a rhetorical question, by the way.” – The Buddy Review of Awesome Felines
“A chubby house cat who thinks he’s a tiger and a human whose writerly ambitions far exceed his talents. Both live in a fantasy world that puts them one harebrained scheme from fame and fortune. If PITB had a print edition we’d recommend it as a birdcage liner.” – The New York Times
“Buddy is an 80s action hero in furry form, a one-cat army whose skill in martial arts is matched only by his razor-sharp wit. We feel privileged to read about his many adventures.” – The Buddinese Shinbun
“The blog works mostly as a celebration of a delusional cat’s ego.” – Associated Press
“Astonishing! With clever and awe-inspiringly beautiful prose, Big Buddy is like a bard expanding the legend of our furry little hero with every post. It’s no wonder Taylor Swift’s cat loves Buddy the Cat so much and wants to share her vast fortune with him.” – El Magnifico Buddenisto
“Buddy the Cat is a legend in his own mind, where his chubby frame becomes ‘meowscle’ and his half-baked plots become ‘genius.’ In that depraved little mind exists a world where kittens plaster his posters on their walls, female cats fight for his affections, and humans argue over who should have the privilege of serving him. Somehow, both cat and human labor under the misconception that what they’re doing is ‘humor,’ but they’re both morons.” – Newsweek
“Like the contents of a particularly foul litter box upended and assembled into crude approximations of words.” – Pitchfork
“Compulsively readable and addicting, like Michael Crichton on crack. Come to think of it, why isn’t there an amusement park based on Buddy and his legend? That’s a billion-dollar idea!”- The Daily Buddy
“Shunned by tigers, nearly murdered by lions, chased out of the White House by thousands of angry Americats and laughed at by rodents. Buddy’s track record is one of infamy and failure, and he’s not cute enough to make up for it. Avoid this blog like the COVID ward of your local hospital.” – The Economist
“So handsome, so kawaii! Budditsu-chan is dreamy!” – CrunchyRoll
“Immature, asinine and frankly offensive, [PITB] chronicles the ‘adventures’ of its titular feline, a delusional lunatic who harbors a single-minded obsession with turkey. When they’re not eating paste or laughing at their own poop jokes, the Buddies are probably smoking catnip, for only drug-addled idiots will find their ‘humor’ amusing.” – GQ
Alex Garland’s latest film is a road trip through the ruins of America as the nation is engulfed in a modern day civil war. It wasn’t so long ago that such a scenario would be unthinkable. Now we wonder if it’s an inevitability.
There’s a moment in Civil War when Kirsten Dunst’s world-weary photojournalist sits down in the ruins of a US industrial park, with tracer fire lighting up the night a few miles away, and turns to Stephen McKinley’s print scribe.
“Every time I got the photo and survived a war zone,” Dunst’s character tells him, “I thought I was sending a warning home: don’t do this. And yet here we are.”
In a movie that works on every level as a warning to the American public not to throw away what we have, what we take for granted, that one quiet moment feels like director Alex Garland speaking directly to the audience, making sure no one can miss the point. Don’t do this.
Dunst, left, and McKinley share a quiet moment in an industrial park as a battle rages a few miles off. Credit: A24
The sad truth is, the United States now seem more divided than at any other point since the original civil war. We’re dangerously close to the abyss, and the people dragging us there are the most ignorant of us. They’re the people who can’t tell you the name of their own congressman and can’t articulate what the three branches of government do (or even what they are), but insist everyone listen with rapt attention as they screech incoherently about politics and demonize those whose views differ.
They’re the people who return the zealots to congress, who populate the extremes and openly fantasize about purging the country of the ideologically impure.
Kirsten Dunst, left, and Cailee Spaeny in Civil War. Credit: A24
They’ve sworn fealty to ideology, abdicating their responsibility to think about things for themselves. Because, frankly, it’s easier to pick a pundit and an alignment, construct a filter bubble in which they never have to be confronted with a fact they don’t like, and be constantly reminded how they should feel about everything from petty culture war issues to conflicts happening a comfortable distance away. That way everything remains neatly in the abstract, and the consequences are someone else’s problem.
But not this time.
Civil War’s cast is phenomenal, but much of the film’s power comes from seeing the familiar become the horrific. Garland illustrates the banality of evil by taking his characters on a journey through the war-torn east coast, past shopping plazas cratered by rocket propelled grenades, waterways filled with bodies and playgrounds on fire. One highway overpass is vandalized with a spray-painted “Go Steelers!” while the bodies of two Americans sway on ropes beneath it.
In refugee camps in Pennsylvania and Virginia, people who could be our neighbors talk quietly around fires while their kids play with soccer balls and chase each other. The film’s main characters, a quartet of journalists trying to get to Washington, DC (where we’re told presidential loyalists shoot members of the press on the spot), marvel when they ride through one idyllic small town where people walk their dogs and hang out in coffee shops as if the country isn’t tearing itself apart.
It’s only when they stop to talk to the proprietor of a small shop that they realize the illusion of normalcy is maintained by an army of sharpshooters keeping watch from the rooftops.
Garland wisely stays away from the specific ideological reasons for the civil war in favor of showing us the fallout.
The president is on his third term. He’s authorized airstrikes on fellow Americans, imprisoned dissidents, put a bounty on journalists and hasn’t offered the public anything more than teleprompter-fed remarks in more than a year. But his authoritarian grip on power is finally fractured when two fed-up coalitions of states break away from the union. The more powerful of the two, the so-called WF (Western Forces), is extremely well-equipped: a shot of one of their camps shows F-35 Raptors, mechanized infantry and heavy lift helicopters.
Dunst’s character in a Western Forces camp. Credit: A24
These aren’t people living on the margins of society, armed with civilian versions of AR-15s. They’re US military, entire divisions defected in opposition to Washington with all the firepower and logistics capacity that entails. Separately, another secessionist coalition led by Florida is making its way up the east coast, seeking to turn the Carolinas and other states to their cause.
The noose is tightening around the president’s neck, even as he insists “the greatest military campaign in American history” under his command has defeated the secessionists, like Baghdad Bob in the Oval Office.
Nick Offerman plays the authoritarian, three-term president who has ordered airstrikes on American citizens and had journalists executed. Credit: A24
As the Western Forces and Florida Alliance push toward D.C., there’s a renewed sense of urgency in symbolism. The president, Wagner Moura’s Joel says early in the movie, will be “dead inside a month.” Both coalitions are intent on reaching Washington and ending the war on July 4th.
“The optics,” Joel tells the other journalists, “are irresistible.”
Thus, the reporters decide to go after “the only story left,” which is to attempt to interview and photograph the president before he’s deposed or killed, despite the very real possibility they’ll be executed on the White House lawn before they can ask a question.
The film’s central characters are Dunst’s Lee Smith, a celebrated photojournalist who has seen it all, Moura’s Joel, the reporter who is partnered with Lee, McKinley’s Sammy, a reporter for “what’s left of the New York Times,” and Cailee Spaeny’s Jessie, a green but fearless 23-year-old who wants to be a war photographer like Lee.
Lee and Jessie meet at the beginning of the film in Manhattan, where both are photographing unrest as people crowd a disaster relief tanker, hoping to fill their containers with water. The fact that one of life’s most essential needs is no longer guaranteed, in New York City of all places, is just the first sign of how bad things have gotten.
Jessie moves in, snapping away as the crowd pushes toward the tanker and NYPD officers try to maintain order. When several people rush the tanker, Jessie gets hit in the face by someone swinging a bat.
Reeling, she stumbles away from the crowd, and Lee immediately mothers her, taking the young woman a safe distance away. She takes off her bright yellow press jacket and gives it to Jessie, then tells her: “If I see you again, you’d better be wearing Kevlar and a helmet.”
Spaeny, left, and Dunst. Credit: A24
They do meet again, the next morning. Lee is surprised to see the younger woman in the back seat of their truck next to Sammy. Furious, she pulls Joel aside. He explains that Jessie had approached him late the previous evening, asking to tag along with him, Lee and Sammy on their trip to DC.
Joel argues that Lee was Jessie’s age when she began her career, but he’s not acting out of the kindness of his heart. He is a man, Jessie is a beautiful young woman, and he has ulterior motives.
Lee’s mouth twitches in disapproval. She sees this fresh-faced, naive 23-year-old, and sees herself before she’s become jaded from a career of documenting humans doing horrific things to each other.
Civil War would be a road trip movie, if road trip movies illustrated camaraderie by shared trauma. Pockets of violence are everywhere. Some involve presidential loyalists fending off advance elements of the Western Forces, but some are civilians who see an opportunity to kill, torture and pillage with impunity.
Dunst is magnificent as Lee, wearing the war photographer’s trauma like armor, her disgust with humanity apparent in her tired eyes. McKinley is the old-school print scribe who can’t quit, even as his body fails him.
“You’re worried I’m too old and too slow,” he tells Lee and Joel early in the film as they drink in the lounge of a Manhattan hotel, imploring them to let him accompany them south to D.C.
“You aren’t?” Lee answers.
“Of course I am,” he admits. “But are you really going to make me explain why I have to do this?”
Wagner Moura’s Joel screams in frustration and rage after a particularly traumatic scene. Credit: A24
Here again, so much of the movie’s power is showing America in a state we only see from a distance through the dispatches and footage of war reporters. As the three of them sip their drinks in the hotel bar, waiting for their stories and photos to transmit over glacial wifi, the power drops.
“That’s every night this week,” Lee sighs.
“They’ll switch to the generators,” Sammy says.
They’re not in the shell of a formerly grand hotel in Baghdad or Damascus, relying on juice from old car batteries. They’re in New York, America’s greatest city, the cultural, media and finance capital of the world, a metropolis that operates on 11 billion watt-hours a day. A devastated, eerily quiet New York which resembles the early days of the COVID lockdown, yes, but New York all the same.
A sniper is pinned down by a civilian who has taken advantage of the lawlessness and chaos to kill fellow Americans. Credit: A24
After watching Civil War, I was disheartened to see the usual rage and incrimination in discussions about the film. Depending on their political backgrounds, people are sure Garland — a native and citizen of the UK — is “a lib” or “a MAGAtard.” Opportunities for thoughtful discussion are derailed in favor of the usual talking point regurgitation.
But the hope is that the sensible are the silent majority, that we aren’t so fattened by domestic stability, security and a feeling of invincibility that we can’t see what’s right in front of our faces. We would do well to remind ourselves that the scenarios we experience only in the safety of fiction still happen all over the world.
As you read this, people are dying of exhaustion and suffering pointless deaths in North Korean and Russian hard labor camps so brutal that we don’t even have a way to place them in context. The people of Haiti are terrorized nightly by ultra-violent gangs who have filled the power vacuum, raping and executing with impunity. Gaza has been bombed to rubble, and its rubble has been bombed to sand. People hoping to escape abject poverty embark on the hard journey to America only to find themselves sold into sexual slavery. Men and women in Asia, desperate to find jobs, arrive at what they think are interviews only to be kidnapped and spirited away into compounds in lawless Myanmar, where they’re forced to sit in front of screens for 20 hours a day running “pig butchering” romance scams on lonely American retirees. If they try to flee, they’re shot.
And just yesterday, a man walked up to a golf course in Palm Beach county, pointed the muzzle of an AK-47 through the chain link fence and tried to assassinate a major party American presidential candidate — the second assassination attempt in three months.
The people who most need to hear Garland’s message are those least likely to heed it, but we can hope. Reality has a funny way of obliterating fantasy, and it’s better for all of us if our delusional countrymen don’t find out the hard way that war is neither fun nor glorious.
Let’s hope Civil War remains a movie, and not a prescient preview of things to come.
Civil War is currently streaming on HBO Max and is available to rent via Apple, Amazon and other online streaming platforms.
Header image: Western Forces units fire rocket propelled grenades at White House loyalists using the Lincoln Memorial for cover. Credit: A24
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Pain In The Bud 