Muahahaha! The Cat Distribution System Has Bestowed A Kitty On My Brother’s Family

Twix the cat is a beautiful Calico living in sunny coastal Italy.

Wary as he may be of them sometimes, Bud is the “family cat” to my nieces.

Now 12 and 8, they’ve wanted a cat for a long time but were vetoed by their parents, since the family was moving to Italy and it appeared my younger niece had allergies.

Well, now they’re finally settled in Italy, tests have confirmed my niece is not allergic to cats, and it turns out their new home comes with a feline.

A beautiful, super-friendly and affectionate Calico named Twix, who was fed, spayed and given veterinary care by the home’s previous family.

“She is super affectionate and lets us pet her a lot,” my brother texted me along with photos of Twix on a window sill and on the grass outside, enjoying scritches from the kids. “Even rolls on her back and has her stomach scratched.”

“Shiiit,” I responded. “Touching the stomach would get you killed with Bud … Well, you got a cat, whether you like it or not.”

The friendly Twix with the girls.

It also looks like Bud will have a potential lady friend. I plan to visit for an extended amount of time and use my brother’s house as a base from which to explore Europe, and there’s just no way I’m going to leave Bud for months, especially when he’ll be 12.

He can handle a long weekend and even a couple of weeks, but months? I don’t think that would be good for either of us, and I worry that he may think I’m not coming back. We have never been separated for that long. He’s coming to Italy with me.

As for Twix, it looks like she’s been living on the property for quite a while. The kids have set up a little shelter for her with blankets. I advised my brother to make sure she has a water bowl that’s refilled regularly with fresh water, they’re feeding her wet food, and I’ll work on getting little Twix inside permanently if she isn’t already a house cat by the time I get there. I can be persistent! It looks like she can come and go as she pleases, so it may not be long before she decides it’s better to be inside and safe.

A friend once taught me that you can “speak Italian” by adding -are (“RA”) onto anything. “Grazie! La felinare!”

Buddy’s Browser History: Ozempic For Cats And Sexy Calicos

Buddy’s browser history provides a window into the depraved mind of everyone’s 683rd favorite feline named Buddy.

Monday, June 9, 2025:

Google search, 6.56am: oh zempic

Google search, 6:57am: ozempic

Wikipedia: Ozempic (pharmaceutical), 7:02am

Google search, 7:07am: ozempic 4 cars

Google search, 7:07am: ozempic 4 cats

Google search, 7:12am: why no ozempic 4 cats?

Pain In The Bud: Latest Stories, 7:44am

Pain In The Bud: Submit Comment: “LIES!!! BUDDY WOULD NEVAR RUN FROM A MOUSES! WHO WRITES THIS RAG?!?”, 7:49am

Google search, 2:33pm: how to get human to give more snax

Google search, 3:11am: hot calico

Google search, 3:14am: sexy calico

Google search, 3:21am: sexy calico new York area

Wednesday, June 11, 2025

Google search, 4:12pm: when do cats get growth spurt

Google search, 4:12pm: when do cats grow into tigers

Google search, 4:15pm: tiger meowscle workout

Thursday, June 12, 2025:

Google search, 1:03pm: turkey

Google search, 1:14pm: turkey

Wikipedia: Turkiye (country)

KFC.com: Order Online, 2:22pm

KFC.com: Colonel’s Original Recipe Bucket, 2:23pm

KFC.com: Confirm Your Order

Friday, June 13, 2025

Google search, 7:16pm: fursat the 13

Google search, 7:16pm: Friday the 13th

Wikipedia: Friday the 13th (film), 7:16pm

Google search, 7;21pm: is jason real?

Google search, 8:16pm: how 2 make human lay on couch

Google search, 8:19pm: how 2 lure human to couch

Google search, 8:23pm: 2nd best thing besides human to sleep on

Google search, 8:29pm: how 2 make human obey

Google search, 8:30pm: r humans stupid?

Google search, 8:44pm: stoopid sport ppl stand in field

Google search, 8:47pm: stoopid sport ppl stand in field and one guy waves stick try to hit ball

Wikipedia: Baseball, 8:52pm

A cat who ran onto the field at Yankee Stadium during a Yankees-Oriolesgame on Aug. 2, 2021. Since the feline, dubbed “rally cat” by the fans, interrupted the game, the Orioles endured a miserable stretch, losing 19 games in a row, while the Yankees went 18-3, including an 11-game win streak. Credit: Bronx Times

Google search, 10:15pm: buddy

Google search, 10:15pm: buddy the cat

Google search, 10:16pm: other buddy the cat

Google search, 10:17 pm: other buddy the cat famous

Google search, 10:19pm: FAMOUS BUDDY THE CAT

Famous Felines: A Site Dedicated To The Biggest Cat Celebrities On The Internet, 10:26pm

/Famous Felines: Buddy (Philadelphia cat)

/Famous Felines: Buddy (cute tabby from Florida

/Famous Felines: Buddy (Phoenix Zoo ocelot)

/Famous Felines: Buddy (TikTok star)

/Famous Felines: Buddy (fictional cat)

/Famous Felines: Buddy (other)

/Famous Felines: Buddy (500 to 599)

/Famous Felines: Buddy (600 to 699)

/Famous Felines: Buddy #683 (New York cat)

Google search, 11:01pm: how 2 get more famous

A Missing Genetic Sequence Leads To Orange Fur In Cats. Could It Be Responsible For Behavioral Differences Too?

Scientists have uncovered the elusive mechanisms behind coat color expression, opening the door to a new question: is fur pigment connected to personality?

When Professor Hiroyuki Sasaki retired, he wasn’t done with science. He just wanted to use it to better understand his cats.

The Japanese geneticist raised more than $73,000 from Japanese and international cat lovers and put together a team, including partners from the US. Then he began the hard work of scrutinizing feline DNA to find out why some cats are orange, and why most all-orange cats are male while virtually all calico and tortoiseshell cats, whose coats have splotches of orange, are female.

It turns out there’s no genetic instruction telling the fur to take on an orange pigment — it’s the absence of a segment of DNA, which governs pigment production, that does it.

In other words, ginger cats are mutants.

Most fully-orange cats are male because the mutation removes the DNA segment in the X chromosome. As males have X and Y chromosomes, they only need the mutation in the single X chromosome for their coats to express in that shade.

Lots of cat lovers swear that coat color and temperament are connected.

Females have an XX chromosomal arrangement, so they need the mutation in both chromosomes to turn tangerine. If the mutation only shows up in one chromosome, you get patches of the color instead of a consistent coat.

That explains why 80 percent of ginger cats are male, and why only one in 3,000 calicos and tortoiseshells are male. A male cat would need an extra X chromosome, XXY, to be born with a calico or tortoiseshell coat. One of the side effects, however, is sterility.

Scientists estimate only one in a thousand male calicos/tortoiseshells can reproduce and pass their unique mutations on.

It’s not just coat color either. The mutation impacts skin and eye color, which is why a ginger cat might have a pink nose compared to the terracotta shade of a void cat or a silver tabby.

Are orange cats really more friendly and silly?

So how does this relate to temperament, and the many people who attest to a particular personality associated with orange cats? Some people say ginger tabbies are more loyal, affectionate and social than cats of other coat colors, but they’re also more prone to doing boneheaded things.

The stereotypes have picked up steam online, where people often share memes depicting orange felines as earnestly derpy, but they may be on to something — or at least, it can’t be ruled out until we know more.

Ginger cats are not the sharpest claw on the paw, according to popular memes.

Because of the missing piece of genetic code, a specific gene, ARHGAP36, isn’t “expressed.” Like so many genes, scientists don’t fully understand everything ARHGAP36 impacts, or how alterations can lead to unexpected changes elsewhere.

“Many cat owners swear by the idea that different coat colours and patterns are linked with different personalities,” Sasaki told the BBC. “There’s no scientific evidence for this yet, but it’s an intriguing idea and one I’d love to explore further.”

Header image via Pexels

Scientists Finally Figure Out Why Some Cats Are Orange, PLUS: Are Street Cats Really ‘Taking Over?’

More Americans say they can’t afford to keep their cats because of inflation, leading to an increase in surrendered and dumped cats in some places.

More than 110 years ago, American geneticist Clarence Cook Little developed a theory explaining why some cats have orange coloring and some don’t.

Now Little has been proven correct thanks to the work of separate teams in Japan and the US, which discovered the mechanism that leads to orange coloring, including fully ginger felines as well as calicos and tortoiseshells.

The explanation may be a bit too heavy on genetics for some readers, but essentially the researchers found the specific gene that leads to the growth or orange fur. They’ve known about the gene for a long time, but didn’t realize the totality of its function. Its official name is ARHGAP36, but for the sake of simplicity, scientists are calling it “the orange gene.”

“The orange gene has a known role in hair follicle development, but scientists didn’t previously know it is also involved in pigment production,” a team of geneticists and biotechnologists wrote in The Conversation, a science publication. “This means that a new pathway for pigment production has been discovered, opening the way for exciting and important research into a basic biological process.”

calico cat relaxing on wooden bench outdoors
In partially orange cats like calicos and tortoiseshells, the blotches of color are the result of imperfect gene copies and a secondary pigment-related gene switching “on and off.” Credit: Mehmet Guzel/Pexels

Ginger cats are usually male, but the pigmant can also appear in female cats due to an error in gene copying which deletes one segment of the orange pigment-producing genetic code.

That’s why calicos and tortoiseshells have orange blotches or mixed orange fur. “[T]he orange gene is persistently switched on in orange areas but is mostly switched off in non-orange areas of a cat’s coat,” the authors wrote.

Are there more strays in 2024?

Time magazine has a story examining the problem of stray cats in America’s urban and suburban population centers, why it’s happening, and what can be done about it.

First, might as well get this out of the way: We don’t know if there are “more” cats. The claim that there are more relies on anecdotes, and there’s no hard data to back that up. You have to be highly motivated to invest the time and money into a proper census like the D.C. Cat Count, and it’s an understatement to say most towns and cities are either not willing to do that, or don’t have the resources.

What we do know is there may be more cats in certain areas, with individual shelters in some places reporting record numbers of surrenders and cats scooped up by animal control.

close up of a stray cat on the metal railing
Rescuers say people who can’t afford food, supplies and veterinary care are surrendering or dumping their cats in larger numbers than in years past. Credit: Dou011fu Tunce/Pexels

The story quotes rescuers who say they’ve seen more surrendered pets, as well as data from Shelter Animals Count, which tallies self-reported information from shelters and rescues. The latter says 32 percent of cats taken in were owner surrenders in 2024, compared to 30.5 percent in 2019.

“It’s a combination of people surrendering their pets and people not adopting because they’re not sure they can take on the financial commitment,” Animal Care Centers of NYC’s Katy Hansen told Time.

Rescuers say that’s reflected in their experiences trapping the felines, who are friendly and acclimated to humans.

The people surrendering their pets cite inflation, not only impacting the cost of essentials like food and litter, but also more expensive veterinary care.

The story additionally includes this eye-popping detail:

“At Veterinary Care Group, a private equity-owned practice in Brooklyn, the cost of spaying or neutering a cat has soared to $850 per animal. By contrast, at the nonprofit veterinary clinic Zweigart recently founded in Brooklyn, the cost of spaying or neutering a cat is $225 and a mid-sized dog is $300.”

The lesson here: Steer well clear of veterinary clinics that aren’t vet-owned or are obtuse about their ownership. Private equity groups don’t buy clinics out of love for animals.

a close up shot of a tabby cat
The cost of spay/neuter procedures ranges dramatically at different veterinary practices. Credit: Tima Miroshnichenko/Pexels

As for solutions to local spikes in stray populations, the story doesn’t offer any. It mentions TNR (trap, neuter, return) but only in the context of a lawsuit against the San Diego Humane Society for its neuter/vaccination program.

That said, there probably isn’t a one-size-fits-all technique. What works for a small town won’t necessarily work in a city, and there are dozens of factors that could influence the prevalence of stray cats and colonies. Still, city councils and town boards don’t need to reinvent the wheel. Chances are if they look, they’ll find a municipality similar to their own where locals have successfully stabilized feline populations.

As for the Buddies, I’d live in my car before giving Bud up. He wouldn’t be thrilled about that situation, and we’d have to head south because the winters here are brutal, but as long as Bud has his servant, he’s good.

A previous version of this post incorrectly described cat chromosomes. The story has been updated to remove the error.

VOTE 4 BUDDY: Today’s The Day!

An optimistic Buddy began election day hoping momentum would carry him to the White House, where he plans to implement dozens of food-related measures.

WASHINGTON, D.C. — With a crowd of more than 60,000 chanting his name, Buddy the Cat made his final appeal to the nation’s felines on Tuesday as they headed to the polls.

“These past four years have been a tragedy,” the candidate told the crowd. “The consistency of wet food has been subpar, dry food has been less crunchy, and Americats are suffering because of inflation, with some snacks costing three times as much as they did in 2020!”

The crowd yowled viciously, expressing its displeasure.

“My opponent, the tyrannical Smudge the Cat, thinks he can hoard all the best snacks for himself while regular Americats make do with grocery brand crunchies,” Buddy continued. “Well I’m here to say ‘Enough!’ I’m here to say that every cat deserves to gorge him or herself on whichever snack they like! I’m here to say no more restrictions on napping spots! I’m here to say that there should be mandatory quiet hours during the dozen scheduled nap times per day!”

The crowd erupted in cheerful meows, waving Americat flags and giant poster-size images of Buddy looking presidential.

President Buddy
A campaign ad for Buddy4Americats.

“I’m also here to tell Vladimir Putin’s cat: Your time has come, Boris! Buddy the Cat is here to kick butt and eat meaty sticks, and I’m all out of meaty sticks!”

“Buddy! Buddy! Buddy!” the crowd roared.

“And to my friends,” Buddy continued, “the tigers of Asia, the lions, leopards and cheetahs of Africa, and our dear fellows, the pumas and jaguars of the Americas, we will form a coalition to bring Boris and his evil servant to heel, liberating Russian cats from the authoritarian rule they have endured for so many years.”

As the crowd chanted his name again, Buddy was hit by a bedazzled pink collar. Waving off half a dozen Sleepy Service agents who moved to quickly close ranks around him, Buddy winked at the Calico who’d thrown the collar, and she fainted.

“Someone get that young lady a bowl of water,” the candidate said, “and make sure her human has my human’s phone number.”

Cats padding out of the rally were enthusiastic and hopeful about their chances.

“Smudge is a corrupt, chubby and inept ‘leader,’ and I use that word in the loosest possible sense,” said Milo, 3, who was voting for the first time. “Buddy’s agenda is the most delicious, and that’s why he’ll win.”

Luna, 5, said Buddy has all the qualities an Americat president should have.

“He’s strong, he understands the importance of naps,” she said, “and he’s so dreamy!”