After 10,000 Years, Dire Wolves Walk The Earth Again

The surprise announcement came from Colossal Biosciences, a company best known for its project to bring back the woolly mammoth.

A US biotech company shocked the world Monday when it announced the births of three dire wolf puppies, bringing back a species that hasn’t lived for more than ten millennia.

Or a version of that species, at least.

Scientists with Colossal Biosciences extracted DNA “from a 13,000 year old tooth and a 72,000 year old skull and made healthy dire wolf puppies,” Colossal CEO Ben Lamm said in a statement.

Of course, it wasn’t that simple.

The dire wolf, Aenocyon dirus, was heavier, stockier and had thicker fur than modern-day gray wolves. In addition, its bite was incredibly strong, generating more force than any living species of canid.

To create the dire wolf puppies, Colossal used the genomes reconstructed from the tooth and skull, spliced them with gray wolf DNA, and made 20 gene edits in 14 genes. Healthy embryos were implanted in three surrogates — large, mixed-breed dogs — and were successfully delivered.

Romulus, one of two male dire wolf pups born late in 2024. Credit: Colossal Biosciences
Remus, who was born at the same time as Romulus. Credit: Colossal Biosciences

Whether the new puppies are officially dire wolves is up for debate and beyond the scope of this post, but just like humans and chimpanzees share 98.7 percent of their DNA, dire wolves and gray wolves share 99.5 percent of their DNA.

The species also existed concurrently with gray wolves and there was interbreeding between the populations, meaning gray wolves already have dire wolf lineage.

As a result, the puppies may be more dire wolf than some are willing to admit. Just how far a “de-extinction” project has to go for the animals to qualify as their namesakes will be debated for years, and there are innumerable questions for which we won’t have answers until the pups grow and scientists monitor their behavior in addition to their physical health.

They won’t behave precisely the way their ancestors did, since they are growing up in a captive environment with teams of specialists constantly monitoring them. The wolves are “essentially living the Ritz Carlton lifestyle of a wolf. They can’t get a splinter without us knowing about it,” Colossal’s chief science officer, Beth Shapiro, told the New York Times.

Whether bringing back dire wolves is a “good” thing is also a topic for another day, at least as far as this post goes. You may disagree, and feel free to say so in the comments, but this is a subject you could write half a library of books on, encompassing ecological, moral and philosophical questions that don’t have easy answers.

It’s made even more complex by the situation we find ourselves in, with our own behavior and relentless expansion killing off more than 70 percent of the world’s wildlife since 1970, according to the World Wildlife Fund. The company wants to use its technology to help critically endangered species, like the red fox, avoid extinction.

Colossal has partnered with leaders in the fields of genetics and bioethics, as well as organizations that specialize in animal welfare. The puppies are in a sizable, custom-built facility in an undisclosed location, secured by “zoo grade” barriers, and the company enlisted the help of the SPCA to create an environment appropriate for them. Colossal says their care regimen will include socialization and the development of pack dynamics.

A newborn dire wolf pup. Credit: Colossal Biosciences

The company has well-publicized projects to bring back woolly mammoths and the dodo, and ultimately, its founders say they want to restore balance in places where apex predators have been brought to extinction by human activity.

“This project demonstrates the awesome potential for advances in genetic engineering and reproductive technologies to recreate lost diversity,” Andrew Pask, a Colossal board member and professor of biosciences at the University of Melbourne, said in a statement. “Apex predators are critical to stabilizing entire ecosystems and their loss from the landscape can have profound impacts on biodiversity.”


The pups are named Romulus, Remus and Khaleesi. That last name is in homage to the character Daenerys Targaryen (Emilia Clarke) from the book series A Song of Ice and Fire, and Game of Thrones, the television adaptation. Dire wolves play a major part in the narrative, and the series is credited with bringing the long-extinct animals back into the popular imagination.

Jon Snow (Kit Harrington) discovers an orphaned dire wolf pup in the first season of Game of Thrones. The pup, who grows into a fierce and massive adult wolf named Ghost, plays a pivotal role in many major events in the series. Credit: HBO
Khaleesi, a female dire wolf, named after the character Daenerys Targaryen from Game of Thrones. Credit: Colossal Biosciences

‘Swift And Lethal’: Cats Have No Defense Against Bird Flu, And It Keeps Showing Up In Their Food

Bird flu is killing cats domestic and wild, in captivity and in nature. Experts are sounding the alarm, warning people not to feed their cats raw food, allow them to drink milk, or let them roam outside where they can easily catch the virus by going after small prey.

Highly Pathogenic Avian Influenza, the clinical name for bird flu, is a danger to all animals, but for cats it’s a virtual death sentence.

Only a handful have survived infection thanks primarily to early diagnosis, intervention and round-the-clock veterinary care. In the vast majority of cases, the virus burns through its feline victims in three or four days.

Bird flu has become even more deadly for felines of late. Of the 126 domestic cats killed by H5N1 since 2022, according to the US Department of Agriculture, half of them have have died in 2025 — and it’s only been three months.

Notably, that total doesn’t include captive wild cats and big cats, such as the 20 pumas, bobcats, tigers and other felids who succumbed to the virus at the Wild Felid Advocacy Center, a sanctuary in Washington state. Nor does it include cats living in the wild, like two pumas in the same state that died in December.

To appreciate the true scope of the problem, the more illuminating statistic may be 82 million, which is the number of chickens “culled” — killed — in the US since 2022 because they were infected or raised at facilities where other birds tested positive for the virus.

Factory farming compounds the matter: more than 1.6 million egg-laying hens and 337,000 “pullets” — chickens less than a year old — were “depopulated” at a single facility in Texas last year. As staggering as those numbers are, Texas’s Department of Agriculture noted the figure merely “accounts for approximately 3.6% of the company’s total flock.”

Per the USDA:

“To provide context on the overall size of the U.S. poultry flock, there are more than 378.5 million egg-laying chickens in the United States. In 2023, more than 9.4 billion broiler chickens and 218 million turkeys were processed in the United States.”

If there ever was an example of putting too many eggs in one basket, this is it. American food supplies are vulnerable with so much concentrated in the hands of so few companies, a lesson the general public is learning the hard way now after eggs peaked at record prices last month. Things have cooled off a bit since then, but shoppers aren’t getting any benefit as grocery chains continue to charge a premium: the nationwide average for a dozen eggs was $5.90 in February, but stores in some states are still charging $10 or more.

It also raises questions about the sustainability and ethics of eating animals. Humans slaughter more than 75 billion chickens every year, and projections indicate there will be three billion more of us by the mid-2080s.

Meat from infected chickens can still end up in your cat’s bowl

Media reports about culling give the impression that those birds are removed from the food chain, but that’s not entirely true. The pet food industry has always cut corners by harvesting meat not fit for human consumption, a category that includes everything from the carcasses of sick animals, to “meat by-products” that can include beaks, hooves, eyes, hearts and other organs.

So while the culled chickens won’t show up in shrink wrap at the grocery store, they are making it into the pet food supply chain. Most pet food is “rendered,” cooked at such high temperatures that potential pathogens have been destroyed.

But an increasingly bigger slice of the market has been claimed by companies selling “premium” raw food — and that’s been the primary infection vector for domestic cats, particularly indoor cats who otherwise would have little or no exposure to the virus. (Cats who spend time outdoors can catch bird flu by preying on infected animals, just as wild cats do, and barn cats have caught it by drinking the milk of infected cattle.)

Cats are mostly lactose intolerant, and should not be given cow’s milk, despite the common misconception that it’s healthy for them.

“The animals that were depopulated could potentially have ended up in the food chain for pets,” Laura Goodman, an assistant professor at Cornell University’s Baker Institute for Animal Health, told NBC News. “It’s not uncommon for substandard meat to end up in the pet food chain.”

That’s what happened to Tim Hanson’s beloved cat, Kira, who died in February after eating raw food from a company called Wild Coast. The company has recalled the product, Boneless Free Range Chicken Recipe. It’s one of four recalls in the last month alone.

Hudson is suing Wild Coast for the veterinary bills — about $8,000 — and said he was devastated that Kira, whom he called “the happiest cat,” is gone. He said he thought he was doing right by her by feeding her the expensive raw food, but now urges people to avoid feeding their cats raw food at all costs.

“I don’t want any more cats dying,” he said. “Hopefully people can learn from Kira’s passing.”

Top image via Pexels. All other images via Wikimedia Commons

Wordy Wednesday: Critically Endangered Orangutan Babies

The palm oil and logging industries have killed so many orangutan mothers, there are now more than a dozen major orangutan orphanages in Borneo and Sumatra. The pressure on orangutans, with whom we share 97% of our DNA, shows no signs of abating.

Orangutans are critically endangered, and the biggest threat to their continued existence comes from the agricultural sector, which has razed 55 percent of the species’ habitat in recent decades.

Jarang, a baby orangutan born in 2023. Credit: Blackpool Zoo

Logging companies clearing irreplaceable, old-growth jungle to claim more land for palm oil plantations have no compunction when it comes to flattening jungles despite the presence of orangutans hiding in the trees. The loggers often shoot the large apes on sight, leaving terrified, traumatized babies still clinging to their dead mothers, or taking them to sell as pets.

Of those left to die, the lucky babies are rescued before they starve and are brought to one of the many orangutan orphanages in Borneo and Sumatra, where they attend “school” to learn how to do everything from climb to forage. It takes at least eight years to teach them how to survive on their own, which is about the time it takes orangutan mothers to do the same job in the wild.

The unlucky babies end up as local pets, sold off to entertainment troupes or shipped off to places like Dubai, where wealthy clients will pay a premium for them.

Caretakers must start by teaching rescued orphans the most basic things, like how to climb and move through the jungle Credit: Borneo Orangutan Survival Foundation
Logos, an orphaned baby orangutan who was rescued in 2023 by the Jakarta Animal Aid Network (JAAN) Credit: International Animal Welfare Fund (IAWF)
Baby Galaksi (Indonesian for galaxy), was found wandering the jungle without his mother in 2021 by a villager in Borneo. He’s now in a “school” that teaches orphaned orangutans how to do everything from evading predators to discerning edible fruit from harmful and poisonous varieties. Credit: Samboja Lestari Orangutan Rehabilitation Centre

So what is palm oil, and why are countries in Asia bulldozing ancient jungles and forests to clear room and make more plantations?

Per the WWF:

“Palm oil has been and continues to be a major driver of deforestation of some of the world’s most biodiverse forests, destroying the habitat of already endangered species like the Orangutan, pygmy elephant and Sumatran rhino. This forest loss coupled with conversion of carbon rich peat soils are throwing out millions of tonnes of greenhouse gases into the atmosphere and contributing to climate change. There also remains some exploitation of workers and child labour. These are serious issues that the whole palm oil sector needs to step up to address because it doesn’t have to be this way.

Palm oil is in nearly everything – it’s in close to 50% of the packaged products we find in supermarkets, everything from pizza, doughnuts and chocolate, to deodorant, shampoo, toothpaste and lipstick.”

Palm oil is in constant demand, and it’s an easy to grow, incredibly efficient crop. Indonesia and Malaysia, the only two countries in the world where orangutans exist, produce 85 percent of the world’s palm oil.

Images of orangutan babies in wheelbarrows are common on social media, but usually stripped of context. Orphanages use the wheelbarrows to bring infants and toddlers to and from “school” every day. Credit: International Animal Rescue
Asoka was found crying in the jungle by a fisherman in Borneo. He was brought to an orphanage in Borneo. Credit: International Animal Rescue’s rehabilitation Centre in Ketapang, West Kalimantan

We share 97 percent of our DNA with orangutans, making the species our second-closest cousins from a genetic standpoint. Some studies claim orangutans are our closest relatives based on our phenotypical similarities.

Orphaned orangutans attending “school” to learn how to survive in the wild. Credit: Borneo Orangutan Survival Foundation
A baby at an orangutan orphanage is fed by a caretaker. Credit: Borneo Orangutan Survival Foundation

Want to read more and learn how to help?

Here are some links to get you started. PITB is a big fan of the Jakarta Animal Aid Network, which successfully pushed Jakarta’s municipal government to ban the incredibly cruel “topeng monyet” monkey street shows:

World Wildlife Fund: Orangutans
Jakarta Animal Aid Network
Borneo Orangutan Survival Foundation
The Orangutan Project
Rainforest Trust

Buddy Visits Leopards, Finds Himself On The Menu

Buddy’s back at it, trying to befriend big cats. Emboldened by his success with the tolerant and wise jaguars, the reckless tabby has his sights set on the savanna and its temperamental predators, the leopards. Can Buddy win the admiration of these notoriously dangerous felids, or will he end up as a light snack for a spotted cat?

VIRUNGA NATIONAL PARK, Democratic Republic of Congo — “What the heck is that?”

A leopardess raised her head in response to her mate’s question, gazing down from the sturdy limb of an acacia tree where she’d taken refuge from the scorching midday sun.

Two hundred yards ahead, a tiny gray cat was padding toward them, picking his way carefully around rocks and occasionally disappearing in the high grass.

“There’s nothin’ that a hundred men on Mars could ever do,” the little feline sang as he walked. “I bless the rains down in Africa! I bless the rains down in…”

The diminutive feline stopped near the base of the tree and looked up at the leopards.

“Jambo!” he meowed enthusiastically. “My name is Budvuvwevwevwe Budyetenyevwe Buddabe Ossas!” he announced. “You can call me Buddy!”

Jambo!

The adult leopards were momentarily stunned until one of the cubs awoke from her nap, spotted Buddy and exclaimed: “Look, mommy, lunch!”

The small cat flashed a wide smile.

“That’s a great idea! I’ve already eaten, but you know what they say: a lunch a day barely keeps the rumbles at bay! I’m a three-lunch cat, myself. So what are we having?”

Another cub piped up.

“That’s not lunch, that’s a snack!” he told his sister.

“And what a cute little snack he is!” the female cub said, gracefully dropping from her napping spot in the tree.

Buddy’s eyes bulged.

“You’re…you’re talking about me?”

The male cub did a squeaky impression of a roar.

“Do you see any other single-serve snacks around?”

Buddy licked his lips, his effort to hide his fear betrayed by his rising hackles and tail, which now resembled a quivering spiked club.

“I…I…I am a cat,” he said in his best impression of an authoritative meow. “I’m practically your cousin!”

The female was just paces away now and moving too fast for Buddy’s liking as he backpedaled.

“The question is,” she said, “are you tasty like cousin Serval or cousin cheetah?”

An image of a leopard cub
Credit: RudiHulshof/iStock

Buddy changed tactics.

“This is an outrage! Not even the tigers tried to eat me! This is…this is, uh, catibalism!”

The cubs were circling him now.

“Mommy, can we have a snack?” the male cub called, looking back at his mother on the tree.

“As long as it doesn’t spoil your dinner later,” came the reply.

“It won’t, mamma!”

Buddy gulped.

The cubs closed the distance, ready to strike, and Buddy was babbling while pleading for his life when the earth itself shook.

Branches jolted and leaves dropped. A flock of birds nesting in a nearby tree took off, silhouettes etching ephemeral geometric patterns in the sky. In the distance, a baboon shrieked a warning to its troop.

The cubs went from aggressive to retreat in the span of an instant, and even their parents looked alarmed, taking off after their young.

Buddy watched them flee, wondering if he should bolt in another direction as something incomprehensibly gargantuan lumbered toward him, shaking the trees.

He’d emptied his bowels by the time a gigantic head poked through the foliage, followed by the rest of the colossal beast. It was gray-skinned, leathery and bizarre, unlike anything Buddy had ever seen.

“Giant space aliens!” he screamed, turning around and running right into a tree trunk.


“Ahhhhh! Don’t eat me!”

Buddy awoke in a sweat, his fur damp in the soupy, stifling heat.

An entire platoon of the peculiar beasts stood around him, their sizes ranging from 25 Buddies in mass to freakishly large individuals sporting pairs of prodigious teeth that looked like scimitars made of bone.

“Einstein’s awake,” one of them rumbled, and the rest turned from stuffing themselves with leaves to get a better look at the Liliputian animal before them.

“What is that thing?” one of them asked.

“It’s a fun-size cheetah!” one exclaimed confidently.

“No, it’s a baby Serval!” another said. “But the color’s all wrong.”

In the distance, a giraffe poked its head above the tree line, pausing to munch on the silky pink flowers of a mimosa tree.

Buddy was saved from hungry leopards by friendly giant space aliens!

Buddy cautiously pushed himself up on his paws. These aliens did not seem interested in eating him.

“Greetings,” he said. “I am a feline, a cat from planet Earth! What planet do you come from?”

There was a pause, then trumpeting, cacaphonic laughter.

“‘What planet are you from?'” one of the great beasts mimicked, sparking a second round of giggles that sounded like the trombone section of an orchestra, if someone had slipped the players psychedelics.

“We are elephants, and this is our home,” said the leader, a magnificent female. “And you, little one, are fortunate we happened by.”

Buddy puffed himself up.

“I think you mean the leopards were lucky,” he said, flexing his meowscles. “They didn’t want to tangle with these guns.”

The elephants chortled. “Can we keep him? He’s funny!”

The matriarch shook her massive head.

“He is far from home, and he should return before he runs into leopards again, or something worse,” she said.

Buddy looked unsure of himself.

“But I’m homies with the jaguars and the tigers! I thought…you know, I could be down with the leopards too. Us big cats gotta stick together, ya know? It’s hard out there for an apex predator. By the way, got any lunch?”

One of the elephants raised her trunk, pointing east toward a herd of intimidating horned beasts.

“Lunch,” she said. “Think you can take them?”

Buddy gulped.

“Go home, little one.”


Buddy’s version of events!

“So anyway,” Buddy said, addressing his human, “that’s how I impressed the leopards, and they made me their king. In fact, they bestowed the honorific ‘Paka mkubwa na mwenye misuli hodari,’ which means ‘great and mighty muscled cat’ in Swahili!”

“Sounds like you had quite an adventure! That’s impressive, Bud!” Big Buddy said.

“It is! It is!” Buddy said, nodding vigorously.

Big Buddy made a whistling sound.

“Was that before or after you peed yourself in terror?”

“What? I…no, I told you, they made me their king! Where did you hear this, this slander?”

Big Buddy reached for his iPad, pulling up images of a terrified Little Buddy running from leopard cubs on the savanna, Buddy running head-first into a tree, and Buddy cowering before a herd of elephants.

“A wildlife tour was nearby during your ‘coronation,’ but this is probably just a gray tabby who looks exactly like you and happened to be right where you were crowned,” he said. “Congratulations, Your Meowjesty!”

Wordless Wednesday: Awesome Photos Of Tigers Swimming!

For tigers, going for a dip on a hot day is pure bliss.

Most cats wouldn’t go near water if even if you lured them with a giant spread of catnip and Temptations on an inflatable table.

But tigers? They love it. Here are some shots of the world’s biggest cats taking a dip.

A Malayan tiger named Azul going for a swim at the Bronx Zoo. Credit: Julie Marsen Laher, Wildlife Conservation Society

Siberian tigers in a tub at a sanctuary in Russia. Credit: digger03/Flickr

This meme made me laugh.

Aasha was rescued from a traveling circus after an inspector found her sickly, suffering from ringworm and only 30 pounds at 8 months old. She’s flourished since she was brought to a sanctuary where she’s been given proper care, a good diet and a calm environment. Aasha is also pictured in the feature photo up top.

A tigress and her cubs cooling off in a river in India. Credit: Sandesh Kadur

Sundarban tigers are a subspecies of the Bengal who live in mangrove forests and are well-adapted to swimming. This Sundarban tiger was spotted on a wildlife tour in India. Credit: Soumyajit Nandy/Wikimedia Commons

This tiger cooled off on a hot day at the Dortmund Zoological Garden in Dortmund, Germany. Credit: Hans Stieglitz/Wikimedia Commons