Oh Oh Oh Ozempic For Our Oh Oh Oh Obese Cats? It’s Close To Reality

In apocalyptic news for house cats everywhere, a pharmaceutical company is kicking off a trial of a GLP-1 drug for felines.

If cats could read newspapers, chances are they’d be gripped by a cold terror right about now, wondering if they’re among the unfortunates to have their yums curtailed by the same weight loss drugs their humans have been gobbling.

As the New York Times reports, a biopharma company headquartered in San Francisco, Okava Pharmaceuticals, is about to begin a trial to determine if GLP-1 drugs can help our chonksters slim down. More than 60 percent of American pets are packing extra pounds, the Times notes, while consequences like diabetes are shortening the lifespans and reducing quality of life for felines and canines.

“It is our belief that the condition of obesity, the condition of being overweight, is by far the number one most significant preventative health challenge in all of veterinary medicine,” Okava founder and CEO Michael Klotsman told the paper.

The upcoming study will include 50 cats. Most will receive a GPL-1 medication while a control group — about one third of the cats — will be given a placebo.

Since cats aren’t exactly known for being cooperative when it comes to taking oral medicine and weekly injections at a veterinary office are impractical, Okava has developed a system with a patch about the size of a microchip that will dispense the weight loss drugs over six months before a tiny cartridge needs to be replaced.

If all goes well with the trial, Okava will seek FDA approval and address other obstacles like convincing caretakers that their little pals can benefit from the feline version of Ozempic, Mounjaro and Wegovy.

That may be easier said than done considering our relationships with our furry friends and the role food plays in things like training, bonding and every day life

For lots of cat caretakers “their main way that they interact with and show their love to their pet often revolves around food,” Dr. Maryanne Murphy, a veterinary nutritionist at the University of Tennessee, told the Times.

How could the dynamic between cat and human change if the flow of yums is reduced to meals only? Will training — for everything from walking on a harness, to entering a carrier and fun tricks like high fives — still work if the reward is just a bit of encouragement or a scratch behind the ear?

An earlier weight loss drug developed for dogs, Slentrol, did not catch on because, as one veterinarian noted, “the main way [people] interacted with their pet was by feeding them, and seeing their excitement and happiness when they were eating the food.”

There’s also the not-so-small matter of cost. GLP-1 drugs are in high demand, and they’re expensive. One in eight Americans has taken Ozempic or one of its competitors. At times, the demand has threatened availability for diabetics, for whom the drugs were developed in the first place.

If the trials are successful and the GLP-1 drugs for pets gain FDA approval — which would require a series of much larger scale, more rigorous studies — the company hopes to offer them to consumers at a cost of about $100 per month per pet.

Even if this iteration of the drug fails, it’s unlikely to derail the larger effort. Vets have been prescribing tiny doses of the human version to cats with diabetes, and perhaps most telling of all, pet obesity continues to rise despite years of efforts by the veterinarian community to get people to play with their pets more and feed them less.

As Dr. Ernie Ward, a veterarian and founder of the Association for Pet Obesity Prevention, told the paper: “We haven’t moved the needle.”


And now we check in with our correspondent, Buddy the Cat. Buddy, what do you think about the possibility of GLP-1 for your species and the end of the proverbial gravy train?

Buddy? Bud? Are we having technical difficulties?

I’m sorry, ladies and gentlemen, we can’t find Buddy the Cat. We’ll resume this segment if and when we manage to locate him.

It’s Never Easy With Bud

Little man’s got acne and won’t let me use a hot compress. Will a topical cream work?

The gross picture you’re looking at is the underside of Bud’s chin.

I knew he’d gotten acne again, but was surprised to see it’s this bad.

So I turned to Google, read a bunch of stuff, and watched a video in which a veterinarian had her arm around calm cat, who allowed her to rub its chin with a warm compress and witch hazel.

These veterinarians with their calm cats! You never see them with a cat like Bud, and I know there’s no magic to their approach because I’ve warned vet techs about him before and have seen them still come away with scratches.

Buddy’s selfie, triggered by the little guy himself when I was trying to get a clear shot of his acne so I could assess how bad it is.

I don’t have any witch hazel, but figured a warm compress could help. I should have known better. He won’t let me do it, just like he won’t let me trim his claws, brush him for more than two seconds at a time, or do just about anything else for his benefit.

When it’s his idea, of course, I can rub his chin until his heart’s content, as well as the top of his head, his cheeks and around his ears. But at all other times? Terrible! Unacceptable!

He is such a pain in the ass. A Pain In The Bud, you might even say. I love him very much and he’s generally a good boy, but what a pain in the ass.

I already have stainless steel bowls for him, so unfortunately this may be my fault for either not cleaning them well enough or not running them through the dishwasher enough to kill off all potential bacteria with heat as well as soap. Normally I wash them by hand with soap between meals/water refilling, and once a week in the dishwasher, but it looks like I’m going to have to be a lot more thorough and really scrub the hell out of them.

In the meantime, can anyone recommend a good topical cream? Bud won’t let me apply anything with a warm cloth or even a soft tissue, but I think I may be able to distract him and apply a topical cream with a Q tip. Then hopefully he’ll realize I’m only trying to help and allow me to apply it.

‘Swift And Lethal’: Cats Have No Defense Against Bird Flu, And It Keeps Showing Up In Their Food

Bird flu is killing cats domestic and wild, in captivity and in nature. Experts are sounding the alarm, warning people not to feed their cats raw food, allow them to drink milk, or let them roam outside where they can easily catch the virus by going after small prey.

Highly Pathogenic Avian Influenza, the clinical name for bird flu, is a danger to all animals, but for cats it’s a virtual death sentence.

Only a handful have survived infection thanks primarily to early diagnosis, intervention and round-the-clock veterinary care. In the vast majority of cases, the virus burns through its feline victims in three or four days.

Bird flu has become even more deadly for felines of late. Of the 126 domestic cats killed by H5N1 since 2022, according to the US Department of Agriculture, half of them have have died in 2025 — and it’s only been three months.

Notably, that total doesn’t include captive wild cats and big cats, such as the 20 pumas, bobcats, tigers and other felids who succumbed to the virus at the Wild Felid Advocacy Center, a sanctuary in Washington state. Nor does it include cats living in the wild, like two pumas in the same state that died in December.

To appreciate the true scope of the problem, the more illuminating statistic may be 82 million, which is the number of chickens “culled” — killed — in the US since 2022 because they were infected or raised at facilities where other birds tested positive for the virus.

Factory farming compounds the matter: more than 1.6 million egg-laying hens and 337,000 “pullets” — chickens less than a year old — were “depopulated” at a single facility in Texas last year. As staggering as those numbers are, Texas’s Department of Agriculture noted the figure merely “accounts for approximately 3.6% of the company’s total flock.”

Per the USDA:

“To provide context on the overall size of the U.S. poultry flock, there are more than 378.5 million egg-laying chickens in the United States. In 2023, more than 9.4 billion broiler chickens and 218 million turkeys were processed in the United States.”

If there ever was an example of putting too many eggs in one basket, this is it. American food supplies are vulnerable with so much concentrated in the hands of so few companies, a lesson the general public is learning the hard way now after eggs peaked at record prices last month. Things have cooled off a bit since then, but shoppers aren’t getting any benefit as grocery chains continue to charge a premium: the nationwide average for a dozen eggs was $5.90 in February, but stores in some states are still charging $10 or more.

It also raises questions about the sustainability and ethics of eating animals. Humans slaughter more than 75 billion chickens every year, and projections indicate there will be three billion more of us by the mid-2080s.

Meat from infected chickens can still end up in your cat’s bowl

Media reports about culling give the impression that those birds are removed from the food chain, but that’s not entirely true. The pet food industry has always cut corners by harvesting meat not fit for human consumption, a category that includes everything from the carcasses of sick animals, to “meat by-products” that can include beaks, hooves, eyes, hearts and other organs.

So while the culled chickens won’t show up in shrink wrap at the grocery store, they are making it into the pet food supply chain. Most pet food is “rendered,” cooked at such high temperatures that potential pathogens have been destroyed.

But an increasingly bigger slice of the market has been claimed by companies selling “premium” raw food — and that’s been the primary infection vector for domestic cats, particularly indoor cats who otherwise would have little or no exposure to the virus. (Cats who spend time outdoors can catch bird flu by preying on infected animals, just as wild cats do, and barn cats have caught it by drinking the milk of infected cattle.)

Cats are mostly lactose intolerant, and should not be given cow’s milk, despite the common misconception that it’s healthy for them.

“The animals that were depopulated could potentially have ended up in the food chain for pets,” Laura Goodman, an assistant professor at Cornell University’s Baker Institute for Animal Health, told NBC News. “It’s not uncommon for substandard meat to end up in the pet food chain.”

That’s what happened to Tim Hanson’s beloved cat, Kira, who died in February after eating raw food from a company called Wild Coast. The company has recalled the product, Boneless Free Range Chicken Recipe. It’s one of four recalls in the last month alone.

Hudson is suing Wild Coast for the veterinary bills — about $8,000 — and said he was devastated that Kira, whom he called “the happiest cat,” is gone. He said he thought he was doing right by her by feeding her the expensive raw food, but now urges people to avoid feeding their cats raw food at all costs.

“I don’t want any more cats dying,” he said. “Hopefully people can learn from Kira’s passing.”

Top image via Pexels. All other images via Wikimedia Commons

Massachusetts Becomes 3rd State To Ban Declawing

The Massachusetts law is a significant victory in the quest for a national ban on the cruel procedure, which involves amputating cat toes at the first knuckle

There’s good news today from Massachusetts, which just joined New York and Maryland in banning cat declawing.

The bill, signed Friday by Massachusetts Gov. Maura Healey, prohibits all declawing surgery except for rare circumstances when it’s medically necessary, like cancer in the nail bed.

Veterinarians who violate the law face fines up to $2,500 and professional discipline if they continue the practice.

Despite its name, declawing is the partial amputation of cat toes, equivalent to cutting off human fingertips at the last knuckle.

a little cat playing
Photo credit: Alex Ozerov-Meyer/Pexels

Declawing changes a cat’s gait, causing the animal pain when it walks, and usually leads to early arthritis. It causes cats to stop using their litter boxes, because the act of standing on and shoveling litter becomes painful for them.

Last but not least, it has a profound psychological impact on felines, making them vulnerable by taking away their primary form of defense. Consequently, cats who are declawed are much more likely to bite than those with intact claws.

Most of all, declawing is cruel and inflicts a lifetime of pain on innocent animals, punishing them for doing what cats naturally do.

Aside from New York, Maryland and Massachusetts, a few dozen cities and counties have banned the procedure, ranging from places like St. Louis, Missouri, to Austin, Texas, and eight cities in California, including Los Angeles and San Francisco.

Bird Flu: Study Warns Virus Has 90% Mortality Rate In Cats, Wild Pumas Succumb To Infection, Sanctuaries On Alert

“If you feed your pet contaminated raw meat or milk, they will likely die. I’m not exaggerating, just giving it to you straight,” one infectious disease specialist warned.

In more disconcerting news from the bird flu front, a new study warns of exceptionally high mortality rates for cats who are infected with the virus.

The study found 89.6 percent of avian influenza cases in cats are fatal, making the virus a virtual death sentence.

That applies to all species of cats, from the true big cats in the panthera genus — tigers, lions, jaguars and leopards — to felines, a broad group that includes domestic cats, lynx, cheetahs, pumas, ocelots, servals, jaguarundis and others.

“We don’t know if the cats are more susceptible than anybody else,” the American Veterinary Medical Association’s Michael Bailey told USA Today. “It’s just the fact they’re exposed to higher viral burdens because of where they go.”

Whether cats are more susceptible is up for debate, but one SPCA chapter said felids of all species are “uniquely vulnerable” to avian influenza because there are so many ways it can be transmitted to them by doing nothing more than what they typically do.

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Cats can be infected by catching and eating birds and mice, drinking raw milk, eating raw meat (including commercial raw pet food), and exposure to infected animals, including cows.

In Washington state, two wild pumas died after contracting the virus from prey, a development Panthera puma director Mark Elbroch called “troubling.”

“It certainly raises eyebrows and makes one wonder: is it indicative of a bigger pattern out of sight?” Elbroch asked, noting pumas are at the top of the food chain in the Pacific northwest.

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To date, as many as 900 cattle herds across the US have tested positive for bird flu, according to the US Department of Agriculture, while two thirds of California’s dairy farms — 660 out of 984 — had confirmed cases as of Dec. 26.

Bird flu was the confirmed cause of death in a house cat from Washington who died after eating Northwest Naturals commercial raw food, which has since been recalled. Three house cats in Texas succumbed to the virus, which they possibly contracted from hunting mice. The bird flu was also responsible for the deaths of two domestic cats in California who drank raw milk, and 20 of 37 wild cats — including a tiger, several pumas, bobcats and a Geoffroy’s cat (pictured at left) — at the Wild Felid Advocacy Center, a sanctuary in Washington.

adorable cream kitten drinking milk outdoors
Contrary to popular belief, cats are typically lactose intolerant. Credit: DHG Photography/Pexels

Veterinarians are warning people to keep their cats indoors and to avoid raw meat diets, which have become more popular in recent years. Cats should not be given cow’s milk anyway, since most are lactose intolerant. As a general rule, kittens should consume milk from their mothers or kitten-specific formula, but should not be given milk from any other source.

“If you feed your pet contaminated raw meat or milk, they will likely die. I’m not exaggerating, just giving it to you straight,” tweeted Dr. Kristen Coleman, an assistant professor at the University of Maryland’s School of Public Health.

While the west coast accounts for the majority of confirmed bird flu infections, the virus continues to spread. A map from the Centers for Disease Control shows where infections have been verified as of late December:

Credit: Centers for Disease Control

Unfortunately, the bird flu outbreak comes on the heels of a heavily politicized pandemic and a major loss in trust in American institutions like the CDC after efforts to obscure the origins of SARS-CoV2, the virus that causes COVID-19.

It’s not clear if the fallout will make Americans less likely to heed warnings about bird flu and other potential viruses, but animal welfare groups and virologists say people can keep their cats safe with a handful of common-sense steps.