science – Pain In The Bud

UK Man Pays $22k To Have Cat Cryogenically Frozen, Hoping To Revive Her In The Future

Using a technology most commonly associated with science fiction, the UK man is banking on a technologically gleaming future where he and his cat can be revived and meet again.

A man in the UK has spent a small fortune on the possibility of reviving his dead cat.

Mark McAuliffe says he was so upset when his 23-year-old cat’s health began to fail that he made arrangements with a Swiss firm to preserve her body when she passed away.

The 38-year-old adopted Bonny, a domestic shorthair, while he was a teenager, and she’s been with him for more than half his life, including his entire adulthood.

Usually when stories like this make the news, they’re about people who preserve their cat or dog’s DNA for cloning.

That’s not what’s happening here.

Bonny has been placed in a cryopreservation unit, which uses liquid nitrogen to freeze her entire body. Freezing a body essentially suspends it in time. Extremely cold temperatures — as close to absolute zero as possible — suspend cellular activity, including decay.

It’s called cryopreservation, and while the concept is most frequently invoked in science fiction, putting a body into cryostasis is real and within the technological capabilities of modern science.

The company McAuliffe paid to preserve his cat is Switzerland-based Tomorrow Bio, which is affiliated with the European Biostasis Foundation. The technology is used for several other purposes in the medical field, the food industry and in certain engineering applications.

McAuliffe is gambling on the future, or a version of it in which people and animals can be revived and repaired, like Lazarus in a lab. But it wouldn’t be much of a future for Bonny if her human wasn’t with her, so McAuliffe has reserved a spot for himself as well, hoping to meet her in better times.

“This cushioned the blow about Bonny’s death,” he said, “because I have got it in the back of my mind that it is not going to be the final goodbye.”

Employees of Tomorrow Bio inspect a liquid nitrogen pod. Credit: Tomorrow Bio

The European Biostasis Foundation runs the cryovaults where clients are kept. The organization told the Daily Mail that it has five “full body patients,” 15 preserved brains, two dogs and eight cats. In addition, more than 700 people have made arrangements to have their own bodies frozen upon death.

There is, of course, a hiccup.

While freezing a body is possible, thawing is not — not without destroying the body.

That’s because ice crystals form and rupture cell walls when the body is brought out of cryopreservation, no matter how slow the process.

The workaround involves using cryoprotectants, essentially a form of anti-freeze that would prevent the formation of damaging ice crystals despite the temperature.

That, however, introduces an entirely new set of problems, including the fact that cryoprotectant is toxic at the levels required for preservation.

Preserving the brain presents an entirely different set of problems, as our neurons and neural pathways begin to decay immediately after death. Our brain topology and neural connections are part of who we are, part of what makes our minds uniquely our own. Neuroscience and cryostasis technology each have a long way to go before scientists can even attempt to thaw a brain.

So by spending almost $22,000 to preserve Bony, and buying a plan to preserve himself (at a cost of $230,000), McAuliffe is banking on major breakthroughs in biology, as well as the ability to precisely control temperatures. To successfully thaw a body without destroying it, the entire body must be warmed at the same time, including all internal organs. That’s a significant technical challenge.

It’s also a gamble on the general shape of the future, placing hope that progress will continue. It assumes we won’t lapse into another dark age, that we won’t lose technology and expertise to devastating wars, plagues or other disasters that could set humanity back decades or centuries.

Finally, there’s a major hurdle that has little to do with science behind cryopreservation. It’s the simple fact that human lives are short, companies that promise centuries of operation can’t guarantee that outcome, and a lot can happen while a person sleeps away those years.

There’s a great short story by the Welsh science fiction novelist Alastair Reynolds about a wealthy man who wakes after centuries of cryosleep to find that the company who managed his crypt went bankrupt. From there it changed hands several times until it ended up in the portfolio of a corporate raider.

So the narrator, expecting to be woken to fanfare, deferential treatment and a bright technological future instead finds himself indebted and facing a reality much different and more depressing than he ever imagined.

I sympathize with McAuliffe, who obviously loves Bonny a great deal, and I see the appeal of becoming a refugee from the past, entering into a cryovault in the hope of emerging into a better future. But man, that’s a huge gamble.

In the meantime, there are plenty of cats who need homes and have a lot of love to give. Every shelter cat is a potential Buddy!

What’s With The Stories Claiming Men Don’t Bond With Or Listen To Their Feline Buddies?

There’s a disconnect between the usually careful language of research studies and the exaggerated claims of news articles.

The headlines over the past few weeks have all been variations on the same riff: cats meow more frequently to male caregivers because we don’t know how to bond with the little stinkers, we disregard their feelings, and we ignore their pleas.

Others are more blunt in their assessment, like a story from YourTango that stated women “bond deeply” with cats, whereas we men are merely “manipulated” by them.

“Other studies have found that women are much better at giving their cats more attention, understanding their cats’ emotions, and are more likely to mimic their cats’ vocalization, too,” the YourTango story claims. “Whereas for men, the same cannot be said. Considering they tend to give affection more sparingly than women, it’s no wonder that the dynamic is different.”

Just picture it: women levitating above the rest of us, sharing their amazing Female Affection with the poor, emotionally starved pet felines who belong to men. If we’re trying to get rid of the “crazy cat lady” stereotype and spread the idea that cats are great companions for every kind of person, this probably isn’t helping.

So what’s the source of these claims?

Apparently a study out of Turkey that involved just 31 cats and their humans. All of the human participants were Turkish, and just 13 of them were male. All were recruited online. (And for some parts of the study, like the analysis of greetings by owner gender, only 26 participants were included because the other five did not submit complete data, including the ages of their cats.)

It’s important to make a distinction between what the study’s authors claim and what the media reports, because they’re almost always two different things.

“Science” doesn’t “say” anything. Science is a method for investigating things we don’t understand. It’s not an entity, it has no opinions, and the only clear conclusion from such a small study is that we need more data.

The research team from the University of Ankara counted more meows directed at the 13 male caregivers in their study compared to the 18 female caregivers. In their paper, the team acknowledged their sample size was too small to draw any conclusions, and lacked the demographic diversity to rule out innumerable potential reasons why those 13 cats meowed more frequently than the 18 cats cared for by women.

Even with a more robust sample size including men of different ages, social classes, and nationalities, correlation is not causation, and it may be that the apparent difference in feline vocalizations disappears with a larger study group that more accurately reflects universal demographics.

Indeed, the study’s authors state clearly that feline greeting behavior is “a complex, multidimensional phenomenon that defies straightforward explanation.” (Emphasis ours.)

The conclusion, as always, is that we need more data, which is one reason why studies must be repeatable.

That nuance doesn’t make it into listicles or stories optimized for maximum shareability on Facebook, so instead we get headlines that present studies as the last word instead of the first tentative steps to understanding a phenomenon.

In case it wasn’t obvious, there is no data to support the claim that men “give attention more sparingly” than women, or that women are better at reading feline emotions. We don’t even have baselines or criteria for those claims. How do we objectively measure “better” when it comes to reading cats, especially when every cat and human bonded pair have their own pidgin “language”? What’s the “right” amount of attention?

Buddy the Cat, a gray tabby cat, with a synthwave background. — “Brrrrrrrruuuuppp!”

As the loyal servant of an infamously talkative cat, I’m not sure gender makes any difference. Bud’s vocal tendencies were already present from kittenhood, and I simply nurtured them by engaging in conversations with him, giving him loads of attention and doting on him.

Often our conversations go like this:

Bud: “Mreeeoww! Mow mow! Brrrrrt a bruppph!”

Me: “I know, little dude. You told me, remember?”

Bud: “Brrrrrr! Brrrruppp! Yerp!”

Me: “Yes, but they’ve tried that already. It’s not just about tokamak design, it’s…”

Bud: “Merrrrrp! Mow mow!”

Me: “No, it’s about plasma containment. No containment, no reaction, no energy gain!”

Bud: “Brrrrr! Mrrrowww! Brupbrupbrrrruppp!”

Me: “Yeah, well that’s just, like, your opinion, man.”

I really do talk about science and science fiction with my cat, since he seems to respond to it. Of course it’s gotta be at least partially due to my tone, but strangely if I talk to him about other abstract things, he acts like I’m bothering him with so much human nonsense.

Regardless, Buddy and I object to the claim that a talkative cat is a disengaged or neglected cat. It’s not that he talks a lot, it’s that he never stops!

Jane Goodall Forever Changed Our Understanding Of Animals

Goodall spent the better part of seven decades with the chimpanzees of Tanzania. Her discoveries were so profound, they forced the scientific community to reevaluate what separates humanity from other animals.

As I’m sure most of you have heard, Jane Goodall passed away Wednesday of natural causes. She was 91.

Goodall’s work was revolutionary and her career was extraordinary. It’s difficult to imagine now, but when Goodall first pitched camp in Tanzania’s Gombe Stream National Park in July of 1960, the scientific community knew virtually nothing about great apes.

Goodall wasn’t exactly welcomed with open arms. Being female and photogenic were the first two strikes against her in the eyes of the establishment.

She was self-taught, didn’t have a degree (she later earned a doctorate at Cambridge), and perhaps her biggest “sins” involved empathy and an attitude more buttoned-up scientists saw as anthropomorphizing the animals.

Goodall with a Gombe chimpanzee. Credit: Wikimedia Commons

Goodall gave the chimps names (a no-no at the time among scientists), carefully observed and recorded their family trees, worked out the obtuse — to human eyes– social hierarchy of primate troops, and witnessed behavior that no one had ever seen before.

She saw friendship, love and loyalty among the chimpanzees, witnessed a bitter war between the Gombe troop and a splinter group, followed families over generations, and saw one chimp die of a broken heart after his mother passed away. (I recommend Goodall’s 1990 book, Through A Window: Thirty Years With The Chimpanzees of Gombe, and the 2002 follow-up, My Life With Chimpanzees, for anyone who wants to read more.)

Her first major contribution, in October of 1960, not only fundamentally challenged our assumptions about animals, it forced us to change the way we regard our own species.

Goodall, observing the chimpanzees from a distance despite the rain that day, watched as a male she named David Graybeard repeatedly dipped blades of grass into the Earth. Curious, Goodall approached the site after Graybeard left, grabbed a few blades of grass and imitated what she’d seen the chimp doing.

She was astonished when she pulled the grass out and the strands were covered in termites. David Graybeard had been eating. He was using a tool to eat!

Goodall at Gombe in the early 1970s. The primatologist secured unprecedented access to the chimpanzees by gaining their trust. Credit: Wikimedia Commons

The discovery was huge because scientists believed tool use was, at the time, limited to mankind. We build and use tools, animals don’t, the thinking went.

When Goodall reported her findings to her mentor, anthropologist Louis Leakey, his prompt response indicated the gravity of her discovery: “Now we must redefine ‘tool,’ redefine ‘man,’ or accept chimpanzees as humans.”

Goodall never stopped working with the chimpanzees of Gombe, and today her formerly humble camp has become a permanent compound where researchers — all inspired by Goodall’s story — continue to study our genetic relatives.

But in her later years, Goodall became known for her activism just as much as her work as a scientist. She traveled constantly, engaging audiences on the subjects of animal conservation, respect for nature and understanding our place in the natural order. It’s a job that has become more necessary than ever as relentless human expansion, habitat fragmentation and human behavior push thousands of species toward extinction.

We lost Frans de Waal, the famous primatologist, in 2024. Now we’ve lost Goodall, and Sir David Attenborough is less than six months shy of his 100th birthday. We’re going to need people to pick up where they left off, and the job is much more difficult than it looks, requiring expertise, charisma and the ability to connect with audiences who know little about the subject matter.

But that’s a problem for another time. For now, let’s remember Jane and appreciate all she’s done over the span of an incredible life and career.

Buddy’s Cat Café Celebrates 2 Years Of Offering Customers The Chance To Lavish Affection And Treats On Buddy

Buddy’s Cat Café and Catnip Lounge has become a neighborhood fixture where feline lovers can enjoy their favorite caffeinated beverages while lavishing snacks and catnip on Buddy himself.

NEW YORK — When Buddy’s Cat Café and Catnip Lounge first opened its doors in late 2023, skeptics were quick to predict its demise.

“A cat cafe featuring only one cat sounds more like the selfish plot of the proprietor feline and less like a legitimate cat cafe experience,” the New York Times sniffed, while the New York Post derided the venture as “one chubby cat’s ludicrous scheme to gorge on endless snacks and catnip while customers line up to shower him with affection.”

Two years later, with a 4.8 out of 5 rating on Google and hundreds of regulars, Buddy’s Cat Café has not only been a success, it’s inspired other felines to open their own single-cat locations.

Mrs. Nakamura watches her students interact with Buddy, affectionately known to them as Badi-chan.

Mrs. Tomoko Nakamura, a teacher at the Japanese Academy of Manhattan, has been taking her class to Buddy’s since the cafe opened.

“Badi-chan very handsome and charming,” Mrs. Nakamura said, smiling as her students giggled and offered an array of crunchy treats to the lounging feline. “All my students love him!”

Sisters Dierdre and Stephanie Sullivan are regulars who say they take their kids to Buddy’s almost weekly.

“Madisyn, Skyelarr and Jaxon just love little Buddy,” Stephanie Sullivan said, calling other cat cafes “a tragedeigh in comparison.”

Buddy and friends during a Tabletop Tuesdays gathering at Buddy’s Cat Café and Catnip Lounge.

Since its opening, Buddy’s has featured an array of themed nights that cater to regulars with shared interests.

On Saturdays a lively crowd of people wearing perms, neon clothes and big shoulder pads flock to the cafe for Retro 80s Night. Sunday crowds gather to watch football with Buddy on the big screen TV, and Tabletop Tuesdays cater to miniature wargamers, with Buddy and his regulars continuing long-running campaigns in Dungeons and Dragons and Warhammer 40K.

One of the most popular themed nights is Freestyle Fridays, when local rappers and hip hop heads gather to spit bars, smoke blunts and collaborate on beats.

DJ Rashid, center, jubilantly hoists Buddy while the others cheer on a recent Freestyle Friday at Buddy’s Cat Cafe.

Buddy after indulging in too much catnip on Freestyle Friday.

Da Ill Collektah, a local underground emcee, rolls catnip blunts for the tabby proprietor so he can fully participate in the levity.

“Oh, that’s good ish!” Buddy said on a recent Friday as he exhaled a nimbus cloud of ‘nip smoke to cheers from the assembled hip hop heads.

“Watch out!” beatsmith Biggity Biggity Bryce exclaimed. “Buddy gonna bless us with a fiyah freestyle!”

Lysander The Lyrical Destroyer, a Brooklyn emcee and longtime “associate” of Buddy, said no other cat cafe could hope to compete.

“Buddy’s cafe got the freshest jams, the livest atmosphere, and the bang bang boogie don’t stop the boogie,” he noted. “But most of all, it’s got Buddy.”

A Missing Genetic Sequence Leads To Orange Fur In Cats. Could It Be Responsible For Behavioral Differences Too?

Scientists have uncovered the elusive mechanisms behind coat color expression, opening the door to a new question: is fur pigment connected to personality?

When Professor Hiroyuki Sasaki retired, he wasn’t done with science. He just wanted to use it to better understand his cats.

The Japanese geneticist raised more than $73,000 from Japanese and international cat lovers and put together a team, including partners from the US. Then he began the hard work of scrutinizing feline DNA to find out why some cats are orange, and why most all-orange cats are male while virtually all calico and tortoiseshell cats, whose coats have splotches of orange, are female.

It turns out there’s no genetic instruction telling the fur to take on an orange pigment — it’s the absence of a segment of DNA, which governs pigment production, that does it.

In other words, ginger cats are mutants.

Most fully-orange cats are male because the mutation removes the DNA segment in the X chromosome. As males have X and Y chromosomes, they only need the mutation in the single X chromosome for their coats to express in that shade.

Lots of cat lovers swear that coat color and temperament are connected.

Females have an XX chromosomal arrangement, so they need the mutation in both chromosomes to turn tangerine. If the mutation only shows up in one chromosome, you get patches of the color instead of a consistent coat.

That explains why 80 percent of ginger cats are male, and why only one in 3,000 calicos and tortoiseshells are male. A male cat would need an extra X chromosome, XXY, to be born with a calico or tortoiseshell coat. One of the side effects, however, is sterility.

Scientists estimate only one in a thousand male calicos/tortoiseshells can reproduce and pass their unique mutations on.

It’s not just coat color either. The mutation impacts skin and eye color, which is why a ginger cat might have a pink nose compared to the terracotta shade of a void cat or a silver tabby.

Are orange cats really more friendly and silly?

So how does this relate to temperament, and the many people who attest to a particular personality associated with orange cats? Some people say ginger tabbies are more loyal, affectionate and social than cats of other coat colors, but they’re also more prone to doing boneheaded things.

The stereotypes have picked up steam online, where people often share memes depicting orange felines as earnestly derpy, but they may be on to something — or at least, it can’t be ruled out until we know more.

Ginger cats are not the sharpest claw on the paw, according to popular memes.

Because of the missing piece of genetic code, a specific gene, ARHGAP36, isn’t “expressed.” Like so many genes, scientists don’t fully understand everything ARHGAP36 impacts, or how alterations can lead to unexpected changes elsewhere.

“Many cat owners swear by the idea that different coat colours and patterns are linked with different personalities,” Sasaki told the BBC. “There’s no scientific evidence for this yet, but it’s an intriguing idea and one I’d love to explore further.”

Header image via Pexels