Tag: health

Oh Oh Oh Ozempic For Our Oh Oh Oh Obese Cats? It’s Close To Reality

In apocalyptic news for house cats everywhere, a pharmaceutical company is kicking off a trial of a GLP-1 drug for felines.

If cats could read newspapers, chances are they’d be gripped by a cold terror right about now, wondering if they’re among the unfortunates to have their yums curtailed by the same weight loss drugs their humans have been gobbling.

As the New York Times reports, a biopharma company headquartered in San Francisco, Okava Pharmaceuticals, is about to begin a trial to determine if GLP-1 drugs can help our chonksters slim down. More than 60 percent of American pets are packing extra pounds, the Times notes, while consequences like diabetes are shortening the lifespans and reducing quality of life for felines and canines.

“It is our belief that the condition of obesity, the condition of being overweight, is by far the number one most significant preventative health challenge in all of veterinary medicine,” Okava founder and CEO Michael Klotsman told the paper.

The upcoming study will include 50 cats. Most will receive a GPL-1 medication while a control group — about one third of the cats — will be given a placebo.

Since cats aren’t exactly known for being cooperative when it comes to taking oral medicine and weekly injections at a veterinary office are impractical, Okava has developed a system with a patch about the size of a microchip that will dispense the weight loss drugs over six months before a tiny cartridge needs to be replaced.

If all goes well with the trial, Okava will seek FDA approval and address other obstacles like convincing caretakers that their little pals can benefit from the feline version of Ozempic, Mounjaro and Wegovy.

That may be easier said than done considering our relationships with our furry friends and the role food plays in things like training, bonding and every day life

For lots of cat caretakers “their main way that they interact with and show their love to their pet often revolves around food,” Dr. Maryanne Murphy, a veterinary nutritionist at the University of Tennessee, told the Times.

How could the dynamic between cat and human change if the flow of yums is reduced to meals only? Will training — for everything from walking on a harness, to entering a carrier and fun tricks like high fives — still work if the reward is just a bit of encouragement or a scratch behind the ear?

An earlier weight loss drug developed for dogs, Slentrol, did not catch on because, as one veterinarian noted, “the main way [people] interacted with their pet was by feeding them, and seeing their excitement and happiness when they were eating the food.”

There’s also the not-so-small matter of cost. GLP-1 drugs are in high demand, and they’re expensive. One in eight Americans has taken Ozempic or one of its competitors. At times, the demand has threatened availability for diabetics, for whom the drugs were developed in the first place.

If the trials are successful and the GLP-1 drugs for pets gain FDA approval — which would require a series of much larger scale, more rigorous studies — the company hopes to offer them to consumers at a cost of about $100 per month per pet.

Even if this iteration of the drug fails, it’s unlikely to derail the larger effort. Vets have been prescribing tiny doses of the human version to cats with diabetes, and perhaps most telling of all, pet obesity continues to rise despite years of efforts by the veterinarian community to get people to play with their pets more and feed them less.

As Dr. Ernie Ward, a veterarian and founder of the Association for Pet Obesity Prevention, told the paper: “We haven’t moved the needle.”

And now we check in with our correspondent, Buddy the Cat. Buddy, what do you think about the possibility of GLP-1 for your species and the end of the proverbial gravy train?

Buddy? Bud? Are we having technical difficulties?

I’m sorry, ladies and gentlemen, we can’t find Buddy the Cat. We’ll resume this segment if and when we manage to locate him.

‘Swift And Lethal’: Cats Have No Defense Against Bird Flu, And It Keeps Showing Up In Their Food

Bird flu is killing cats domestic and wild, in captivity and in nature. Experts are sounding the alarm, warning people not to feed their cats raw food, allow them to drink milk, or let them roam outside where they can easily catch the virus by going after small prey.

Highly Pathogenic Avian Influenza, the clinical name for bird flu, is a danger to all animals, but for cats it’s a virtual death sentence.

Only a handful have survived infection thanks primarily to early diagnosis, intervention and round-the-clock veterinary care. In the vast majority of cases, the virus burns through its feline victims in three or four days.

Bird flu has become even more deadly for felines of late. Of the 126 domestic cats killed by H5N1 since 2022, according to the US Department of Agriculture, half of them have have died in 2025 — and it’s only been three months.

Notably, that total doesn’t include captive wild cats and big cats, such as the 20 pumas, bobcats, tigers and other felids who succumbed to the virus at the Wild Felid Advocacy Center, a sanctuary in Washington state. Nor does it include cats living in the wild, like two pumas in the same state that died in December.

To appreciate the true scope of the problem, the more illuminating statistic may be 82 million, which is the number of chickens “culled” — killed — in the US since 2022 because they were infected or raised at facilities where other birds tested positive for the virus.

Factory farming compounds the matter: more than 1.6 million egg-laying hens and 337,000 “pullets” — chickens less than a year old — were “depopulated” at a single facility in Texas last year. As staggering as those numbers are, Texas’s Department of Agriculture noted the figure merely “accounts for approximately 3.6% of the company’s total flock.”

Per the USDA:

“To provide context on the overall size of the U.S. poultry flock, there are more than 378.5 million egg-laying chickens in the United States. In 2023, more than 9.4 billion broiler chickens and 218 million turkeys were processed in the United States.”

If there ever was an example of putting too many eggs in one basket, this is it. American food supplies are vulnerable with so much concentrated in the hands of so few companies, a lesson the general public is learning the hard way now after eggs peaked at record prices last month. Things have cooled off a bit since then, but shoppers aren’t getting any benefit as grocery chains continue to charge a premium: the nationwide average for a dozen eggs was $5.90 in February, but stores in some states are still charging $10 or more.

It also raises questions about the sustainability and ethics of eating animals. Humans slaughter more than 75 billion chickens every year, and projections indicate there will be three billion more of us by the mid-2080s.

Meat from infected chickens can still end up in your cat’s bowl

Media reports about culling give the impression that those birds are removed from the food chain, but that’s not entirely true. The pet food industry has always cut corners by harvesting meat not fit for human consumption, a category that includes everything from the carcasses of sick animals, to “meat by-products” that can include beaks, hooves, eyes, hearts and other organs.

So while the culled chickens won’t show up in shrink wrap at the grocery store, they are making it into the pet food supply chain. Most pet food is “rendered,” cooked at such high temperatures that potential pathogens have been destroyed.

But an increasingly bigger slice of the market has been claimed by companies selling “premium” raw food — and that’s been the primary infection vector for domestic cats, particularly indoor cats who otherwise would have little or no exposure to the virus. (Cats who spend time outdoors can catch bird flu by preying on infected animals, just as wild cats do, and barn cats have caught it by drinking the milk of infected cattle.)

Cats are mostly lactose intolerant, and should not be given cow’s milk, despite the common misconception that it’s healthy for them.

“The animals that were depopulated could potentially have ended up in the food chain for pets,” Laura Goodman, an assistant professor at Cornell University’s Baker Institute for Animal Health, told NBC News. “It’s not uncommon for substandard meat to end up in the pet food chain.”

That’s what happened to Tim Hanson’s beloved cat, Kira, who died in February after eating raw food from a company called Wild Coast. The company has recalled the product, Boneless Free Range Chicken Recipe. It’s one of four recalls in the last month alone.

Hudson is suing Wild Coast for the veterinary bills — about $8,000 — and said he was devastated that Kira, whom he called “the happiest cat,” is gone. He said he thought he was doing right by her by feeding her the expensive raw food, but now urges people to avoid feeding their cats raw food at all costs.

“I don’t want any more cats dying,” he said. “Hopefully people can learn from Kira’s passing.”

Top image via Pexels. All other images via Wikimedia Commons

‘Why Are Cats Such A Medical Black Box?’ New York Times Columnist Asks

Veterinary science and research still focuses primarily on dogs, but scientists are trying to change that and help us better understand how to care for our little feline buddies.

“It’s just a cat.”

I’ve heard that so many times, and if you’re a cat lover, you probably have too.

It’s an insinuation that cats are throwaway animals, fungible pets who can be replaced by others of their species because, some people claim, they don’t express themselves as individuals, never really warm to humans in the first place, and besides, it’s not like they have emotions.

Countering those persistent myths is one of the reasons I write this blog. I still didn’t have a full appreciation for how singular and smart cats can be until I brought Buddy home. I never fathomed the depth of his emotions, the strength of his convictions or his willingness to make his opinions known about everything.

In some ways, I’m still shocked at how much he communicates and how well we understand each other.

However, one of my biggest fears is not doing right by him, especially missing signs of declining health as he gets older.

That’s the subject of a column today in the New York Times, in which science write Emily Anthes recalls the subtle signs that her cat, Olive, was sick, and the veterinarian’s assessment that she wasn’t just ill, she was on death’s door.

Credit: Pexels

Anthes points out that, to this day, veterinary training uses canines as the default, and treatments for cats are often just adapted from treatments for dogs, even if there’s no data suggesting those methods actually work for feline patients.

“My anatomy book was ‘Anatomy of the Dog,’” Maggie Placer, veterinary science programs manager at EveryCat Health Foundation, told the Times. “We had PowerPoints and supplements for the cats.”

The differences go beyond body plan, organs and behavior: drugs that work for dogs can be ineffective or dangerous for cats. Treatments otherwise regarded as effective in other animals could be harmful to felines too.

“It’s not reasonable to assume that everything that works in a dog will work in a cat,” Bruce Kornreich, director of the Cornell Feline Health Center, told Anthes. “There’s a lot that we still need to learn.”

Credit: Pexels

The situation with feline veterinary science mirrors the gap in behavioral studies between cats and dogs.

Over the past decade, research teams in countries like the US and Japan have made efforts to close the gap by recognizing that studies must be crafted to feline points of view, and that laboratories are not suitable places for studying the behavior of such notoriously territorial animals. Cats behave differently outside of their environments, rendering data useless if it’s captured in settings where kitties are stressed, unsure of themselves or even just miffed that they’re not at home enjoying a nap.

There are unique challenges when it comes to studying effective veterinary treatments in cats as well. Primary among them is feline stoicism, an evolutionary adaptation.

Simply put, cats will do everything they can to mask injury and sickness because they don’t want to become prey. Unfortunately that means by the time a cat cannot conceal an ailment anymore, the disease or injury has progressed. Even if a cat has lived indoors her entire life, the directive to disguise her pain is hardcoded into her DNA.

Anthes’ cat, Olive, didn’t make it. But her litter mate is chugging along, and to help advance the cause of understanding cat health, Anthes submitted both cats’ fur clippings to geneticist Dr. Elinor Karlsson’s Darwin’s Cats, a “non-profit community science project” that uses DNA submitted by cat owners to better understand our furry friends and unlock the secrets of their health and behavior.

Let’s hope that such projects spark a renaissance in studying cat health, like they have with research into feline behavior, so we can do right by our little buddies.

Bird Flu: Study Warns Virus Has 90% Mortality Rate In Cats, Wild Pumas Succumb To Infection, Sanctuaries On Alert

“If you feed your pet contaminated raw meat or milk, they will likely die. I’m not exaggerating, just giving it to you straight,” one infectious disease specialist warned.

In more disconcerting news from the bird flu front, a new study warns of exceptionally high mortality rates for cats who are infected with the virus.

The study found 89.6 percent of avian influenza cases in cats are fatal, making the virus a virtual death sentence.

That applies to all species of cats, from the true big cats in the panthera genus — tigers, lions, jaguars and leopards — to felines, a broad group that includes domestic cats, lynx, cheetahs, pumas, ocelots, servals, jaguarundis and others.

“We don’t know if the cats are more susceptible than anybody else,” the American Veterinary Medical Association’s Michael Bailey told USA Today. “It’s just the fact they’re exposed to higher viral burdens because of where they go.”

Whether cats are more susceptible is up for debate, but one SPCA chapter said felids of all species are “uniquely vulnerable” to avian influenza because there are so many ways it can be transmitted to them by doing nothing more than what they typically do.

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Cats can be infected by catching and eating birds and mice, drinking raw milk, eating raw meat (including commercial raw pet food), and exposure to infected animals, including cows.

In Washington state, two wild pumas died after contracting the virus from prey, a development Panthera puma director Mark Elbroch called “troubling.”

“It certainly raises eyebrows and makes one wonder: is it indicative of a bigger pattern out of sight?” Elbroch asked, noting pumas are at the top of the food chain in the Pacific northwest.

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To date, as many as 900 cattle herds across the US have tested positive for bird flu, according to the US Department of Agriculture, while two thirds of California’s dairy farms — 660 out of 984 — had confirmed cases as of Dec. 26.

Bird flu was the confirmed cause of death in a house cat from Washington who died after eating Northwest Naturals commercial raw food, which has since been recalled. Three house cats in Texas succumbed to the virus, which they possibly contracted from hunting mice. The bird flu was also responsible for the deaths of two domestic cats in California who drank raw milk, and 20 of 37 wild cats — including a tiger, several pumas, bobcats and a Geoffroy’s cat (pictured at left) — at the Wild Felid Advocacy Center, a sanctuary in Washington.

adorable cream kitten drinking milk outdoors
Contrary to popular belief, cats are typically lactose intolerant. Credit: DHG Photography/Pexels

Veterinarians are warning people to keep their cats indoors and to avoid raw meat diets, which have become more popular in recent years. Cats should not be given cow’s milk anyway, since most are lactose intolerant. As a general rule, kittens should consume milk from their mothers or kitten-specific formula, but should not be given milk from any other source.

“If you feed your pet contaminated raw meat or milk, they will likely die. I’m not exaggerating, just giving it to you straight,” tweeted Dr. Kristen Coleman, an assistant professor at the University of Maryland’s School of Public Health.

While the west coast accounts for the majority of confirmed bird flu infections, the virus continues to spread. A map from the Centers for Disease Control shows where infections have been verified as of late December:

Credit: Centers for Disease Control

Unfortunately, the bird flu outbreak comes on the heels of a heavily politicized pandemic and a major loss in trust in American institutions like the CDC after efforts to obscure the origins of SARS-CoV2, the virus that causes COVID-19.

It’s not clear if the fallout will make Americans less likely to heed warnings about bird flu and other potential viruses, but animal welfare groups and virologists say people can keep their cats safe with a handful of common-sense steps.

With Bird Flu Spreading, It’s Probably A Good Idea To Keep Your Cats Inside

So far there are no cases of cats infecting humans, but a new study published Tuesday warns the virus easily mutates in infected felines.

Health officials have identified at least five cases of domestic cats infected with H5 bird flu in California, and they’re warning of multiple vectors of transmission now that both outdoor and indoor cats have been infected.

Two cats were infected after drinking raw milk from a dairy farm in Fresno, California, according to the Los Angeles Department of Public Health. That’s also how a dozen barn cats died in April after drinking raw milk from infected cows on a Texas dairy farm, the CDC said.

But three other cats who tested positive for bird flu were indoor-only, lived in the same home, and did not consume raw milk, authorities said. They’re looking into the possibility that the felines were infected through raw meat or by hunting mice.

So now it’s not only confirmed that cats are vulnerable to highly pathogenic avian influenza, or HPAI H5N1, but that they can be infected in different ways.

To be clear, it’s not a cause for panic and it doesn’t mean people should isolate from their cats, but it does mean we should be smart and considerate when it comes to protecting our pets and reducing the possibility that they can be infected.

Because millions of felines live with humans, the fear is that they can pass the virus onto us. So far there have been no confirmed cases, but a study published on Tuesday confirmed that the virus can easily mutate in cats. That means the more domestic cats are infected, the greater chance the virus mutates in a way that allows it to “bridge” to humans.

At least two people — one in Wisconsin and one in Louisiana — have tested positive for the virus and were hospitalized this week. One worked on a farm and the other may have consumed raw milk. In the meantime, health officials are monitoring the people whose three cats were infected, and they’re urging people to take precautions.

“To avoid the spread of disease, including H5 bird flu, we strongly encourage residents and their pets to avoid raw dairy and undercooked meat products, limit contact with sick or dead animals, report sick or dead birds, and keep pets or poultry away from wild animals and birds,” said Dr. Barbara Ferrer, director of the Los Angeles County Department of Public Health.