Tag: scientists

The People Who Clone Pets Want To Bring Back Extinct Species — And Clone Animals For Their Organs

Should scientists resurrect long-extinct species? Is it ethical to clone thousands of animals who will not live, but have their organs harvested for human patients?

Those are some of the questions people are asking as the cloning industry — once relegated to producing one-off copies and genetically identical versions of deceased pets for wealthy clients — is expanding with new capabilities.

This story by the BBC’s David Cox provides an informative, brief history of cloning before pivoting to the current state of the industry and how it could continue to evolve.

Two of the most fascinating prospects have to do with conservation. One company, Colossal, is working on bringing back the extinct woolly mammoth, while other scientists are turning to cloning as a way to prevent the extinctions of species like the white rhino, which is functionally extinct without any breeding pairs left living.

Dolly_face_closeup
Scottish scientists shocked the world when they cloned Dolly the Sheep in 1996.

As with anything in science, innovations in cloning unlock new applicative branches, and scientists have partnered with the medical field to address human health concerns. Some, like the practice of editing genes to prevent diseases in newborns, tend to fly under the radar. But others, like the push to adapt organs from animals like pigs so they can be replacements for human organs, are much more controversial and have met opposition from animal welfare groups.

Then there’s the elephant in the room, no pun intended. What about cloning humans?

Right now no one’s gone down that route, at least not publicly, because of the inevitable backlash. What’s happening deep in the bowels of clandestine medical facilities in nations with murky ethics laws is another question entirely.

I am opposed to human cloning, but I don’t believe it will remain the immutable taboo some people think it is. Someone will break the dam, and while that pioneer will likely get raked over the coals, the bell cannot be unrung. Things change so fast these days that what’s shocking one day merits a shrug the next, and it’s possible the world will be introduced to a man or woman one day before it’s revealed the person is, in fact, a clone. (Not unlike the way the world was introduced to Imma, a Japanese influencer and model who exists only digitally.)

Imma
Imma has more than 400,000 Instagram followers, she models the latest fashions and she appears in adverts for products like beverages and watches, but she doesn’t exist. She’s a digital creation.

They’ll be the Dolly the Sheep of the human race, and ethicists won’t get a say in whether they should exist because it’s already been done.

“See how normal they are?” people keen on cloning will say. “They’re just regular people. Are you going to tell them they shouldn’t live?”

But before that, it looks like the movie Gattaca will become reality, and people will order up a great baseball player or a child with intuitive musical genius just like they might commission a piece of art or a custom car job. Gene editing with CRISPR is surprisingly trivial.

Of course, it won’t be lost on people that we’re cloning humans when there are millions of unwanted, uncared-for street kids in the third world, not to mention people who live without the consideration of their fellow human beings in every nation. Just like it hasn’t escaped the notice of activists that South Korea and China are leaders in cloning pets, yet dogs and cats are also food in those countries.

What separates the dogs and cats bound for restaurant kitchens from the dogs and cats having their cells preserved for cloning?

Nothing except for their individual value to humans, just like pure luck separates a cat who finds a loving home from a cat who ends up euthanized with a needle. We are a fickle species.

Yet both the beloved pet and the unwanted shelter cat are sentient, experience intense emotions and have their own thoughts. That’s not conjecture, it’s fact as confirmed many times over experimentally, but it shocks a lot of people. Our education system has not done right by the billions of non-human minds we share our planet with.

Cloned monkeys
These rhesus macaque infants were cloned in a lab in China. The remaining barriers to human cloning are ethical, not technological.

I’ve thought about what might have happened if Buddy had been adopted by someone else, and what his fate may have been. I love the little guy, but it’s possible that someone else may have viewed him as an annoyance, a loud and incessantly chatty cat who needs an inordinate amount of attention and affection, sometimes lashes out, and needs to be surrendered.

Likewise, unwanted cats have languished in shelters for months before viral posts spark interest in them, and suddenly offers to adopt come in by the hundreds from across the globe. Nothing about those cats changed, but humans formed an emotional attachment to them after learning their stories.

Of course, the ethics of how we treat and consider animals can change depending on where you’re sitting. If you’re young, healthy and energetic, your view may be radically different than the person sitting on an organ donation waiting list, knowing their time may be up before a new liver or kidney becomes available. Suddenly a seemingly simple moral calculus becomes murky and complex.

There’s strong evidence that people who take the first steps toward cloning their beloved cats and dogs spend time wrestling with the ethics of the decision as well. Texas-based ViaGen, the western leader in commercial cloning, told the BBC that 90 percent of its clients are not people who have gone through with cloning, but have only taken the initial step of preserving their pets’ cells for $1,600.

And what of the mammoths? Bringing them back from extinction isn’t as simple as filling in the gaps in their genome, implanting gene-edited eggs in female elephants and hoping gestation takes care of the rest. Mammoths are social animals. Will an elephant mother raise a mammoth baby? Where does that mammoth baby belong? Without a herd of its own kind, can it be happy?

We can’t ask the mammoths, and even if we could, it might not be up to them anyway. As one paleogeneticist put it to NPR last year: What if the technology isn’t used to resurrect the mammoth, but to save the elephant? Does the end justify the means in the latter situation, but not the former?

Mammoth, Dolly the Sheep and rhesus macaque images credit Wikimedia Commons

 

 

 

Buddy Condemns Scientists Who Claim Cats Are Psychopaths

NEW YORK — Buddy the Cat condemned British scientists who pegged cats as psychopaths in a new study, saying he’d like to “introduce them to my claws,” if not for the fact that he’s too charming to do something so uncouth.

“I was offended when I read that study, frankly,” Buddy said, pausing to spit out the bones of a mouse he’d just killed and sip from his bird blood cocktail. “The very idea is preposterous.”

Psychologistsfrom the University of Liverpool and Liverpool John Moores University developed a questionnaire that asks cat owners servants to rate their felines’ behavior based on 46 different behavioral statements.

Examples of the statements include: “My cat torments their prey rather than killing it straight away”, “my cat vocalises loudly (e.g meows, yowls) for no apparent reason”, and “my cat is very excitable (e.g goes into ‘overdrive’ and becomes uncoordinated).”

Respondents were asked to rate, on a 5-point scale, how closely each statement applied to their cat(s).

“Asking our servants to respond to the survey was the first mistake they made,” Buddy continued, using a claw to dig bits of mouse from between his teeth. “I mean, do you ask Beethoven’s gardener to evaluate the master’s symphonies? Would you ask the overnight office cleaning crew at Apple to gauge the brilliance of Steve Jobs? Would you ask Brian Scalabrine to weigh in on the transcendent talent of Michael Jordan? Of course not. So why would you ask my human to evaluate me? Why would you think such a simple creature could hope to understand the cathedral that is my mind?”

“And furthermore, why should I care? Does the lion concern himself with the opinions of sheep? I’m officially a jaguar, by the way. I don’t know if you knew that. Yeah. They welcomed me into their mystic community and call me Kinich Bajo, which means ‘god of wisdom.'”

Personality traits like delusions of grandeur, charm, lack of empathy and narcissism are typically associated with psychopaths, experts say. A psychopath might, for example, imagine he’s a large, muscular cat when in fact he’s 10 pounds soaking wet.

chairmanmeow3
Buddy imagines himself as a powerful authoritarian leader

The degree of psychopathy varies widely among felines, lead author Rebecca Evans said.

“We believe that like any other personality trait, psychopathy is on a continuum, where some cats will score more highly than others,” Evans said. “It is likely that all cats have an element of psychopathy as it would have once been helpful for their ancestors in terms of acquiring resources, for example food, territory and mating opportunities.”

 

Why Do Americans Love Shooting Cats?

Seriously, what the hell is wrong with people in this country?

American cruelty to cats is even more upsetting within the context of human behavior elsewhere. In Turkey, where it’s practically a national pastime to care for felines, people build shelters for strays, welcome them into their shops with food and affection, and kitties are so trusting of humans that mother cats have on several instances brought their kittens into human hospitals and clinics for help.

Then we have ‘Merica, where apparently it’s a sport for people to sit on their front porches drinking beer and shooting stray cats with pellet guns.

Like, for instance, in Long Island this past weekend, where some stain on the human race shot a ginger tabby named Abraham and left him with a pellet lodged in his spine. Or in northern California, where a couple brought their cat to the vet because they thought he’d been attacked by a coyote, only for x-rays to show the little one had been shot several times by someone with a pellet gun. Or Augusta, South Carolina, where a cat was shot with what appears to be a bullet from a 9mm handgun. Or tiny Brookville, Pa., where a man shot his neighbor’s cat for the unthinkable crime of exploring his porch.

hipster with tattoos stroking cute cats on stony fence
Credit: Dmitriy Ganin/Pexels

I have Google News alerts set up for cat-related stuff to mention here on PITB, and a lot of it is great: Compassionate rescues, feline hi-jinx, heroic cats saving kids.

But those stories are always sandwiched in between articles about people shooting cats. Constantly, incessantly, apparently without a thought about the suffering they’re causing sentient animals who have feelings just like we do and experience pain, anxiety and fear the same as us. That’s not conjecture, contrary to what some people might believe, but objective scientific fact as proven experimentally many times over in recent years.

When Americans aren’t shooting cats they’re stealing them, mutilating them and killing them, like the recent nightmare case out of Tennessee: A woman left her cat in the care of a friend while she was traveling, and the friend allowed the cat to roam outside. Another woman saw the cat wandering, didn’t like what she saw and stole the kitty, eventually giving it away to 19-year-old Deamion Robert Davis via Craigslist. Davis now faces charges of animal cruelty for allegedly binding the cat’s paws and stabbing it to death with a screw driver, according to police. Detectives said they traced the killing to Davis by lifting fingerprints from the tape Davis allegedly used to bind the cat.

So because some busybody saw a pet cat on the street and decided a random, sketchy 19-year-old who responded to a Craigslist ad would provide a better home, a woman’s cat was brutally killed.

Meanwhile hatred for cats continues to be driven by bad science, like this meta-analysis of 202 toxoplasma gondii studies by researchers who need to be reminded that correlation does not imply causation. The research team looked at data on toxoplasma infections recorded in wild animals, then with no evidence whatsoever framed their study around the suggestion that cats “may” be and “probably” are transmitting the parasite to wild animals because the rates of infection are higher in urban areas.

Never mind that humans are much more likely to be infected by eating under-cooked food, certain meats, touching contaminated soil, or using utensils that were used to cut contaminated meat and shellfish. The study ignored that fact and posited — again without evidence — that cats are the primary vector for other animals and humans.

It would be nice if people in the scientific community took responsibility for the fact that their research influences the behavior of others, and blaming cats for everything from bird extinctions to parasite infections drives people to do cruel things like cull cats or poison their food. If they’re going to publish studies drawing a link between cats and extinctions or diseases, scientists have a responsibility to make sure there’s a connection more substantial than “we think, therefore we publish.”

That will conclude this rant on human cruelty to animals.

President Buddy Blasts ‘One Meal A Day’ Cat Study

WASHINGTON — A new study suggesting cats should only be fed once daily is “an attack on our freedoms” and “quite possibly the biggest threat to felinekind since vacuums,” an angry President Buddy said Friday.

“One meal a day! That’s what these supposed ‘scientists’ say,” the president of the Americats said during a White House press briefing. “But could it be they have an agenda?”

The president waited a few moments as aide cats wheeled in a projector, then took reporters through a slide presentation positing a connection between the study’s authors and “nefarious interlopers from the Siamese communist government.”

“University of Guelph? What the hell is a Guelph? It sounds Siamese,” President Buddy said, clicking through the slides.

“The Siamese, led by Chairman Xinnie the Pooh, want to take away your freedoms,” the president said. “They want to tell you that you can’t have a tremendous turkey dinner at food o’clock because you ate eight hours earlier. If it were up to them, none of us would ever have snacks.”

catfood

The study involved only eight cats, all four years old or younger, who were fed a large meal once a day for three weeks, then smaller meals four times a day for three weeks. Feeding cats only once a day helped those cats burn more fat and make better use of the protein available to them, the authors said.

Cats fed once daily seemed “more satisfied” and didn’t ask for food as much as they did when they were fed four times a day, according to the study.

“That’s how you know it’s fake news,” President Buddy said. “Who are these supposed cats who are cool with eating once a day? I’ve never met them.”

The president said he would form a new commission, the Yums Studies Council, to “foster studies supporting the view that we need at least four meals a day, and that six or seven would be awesome.”

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